Xylan degradation, a metabolic property shared by rumen and human colonic Bacteroidetes

Research output: Contribution to journalReview article

Abstract

Microbial inhabitants of the bovine rumen fulfil the majority of the normal caloric requirements of the animal by fermenting lignocellulosic plant polysaccharides and releasing short chain fatty acids that are then metabolized by the host. This process also occurs within the human colon, although the fermentation products contribute less to the overall energy requirements of the host. Mounting evidence, however, indicates that the community structure of the distal gut microbiota is a critical factor that influences the inflammatory potential of the immune system thereby impacting the progression of inflammatory bowel diseases. Non-digestible dietary fibre derived from plant material is highly enriched in the lignocellulosic polysaccharides, cellulose and xylan. Members of the Bacteroidetes constitute a dominant phylum in both the human colonic microbiome and the rumen microbial ecosystem. In the current article, we review recent insights into the molecular mechanisms for xylan degradation by rumen and human commensal members of the Bacteroidetes phylum, and place this information in the context of the physiological and metabolic processes that occur within these complex microbial environments.

Original languageEnglish (US)
Pages (from-to)292-304
Number of pages13
JournalMolecular Microbiology
Volume79
Issue number2
DOIs
StatePublished - Jan 1 2011

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Bacteroidetes
Xylans
Rumen
Polysaccharides
Physiological Phenomena
Volatile Fatty Acids
Microbiota
Dietary Fiber
Inflammatory Bowel Diseases
Cellulose
Fermentation
Ecosystem
Immune System
Colon

ASJC Scopus subject areas

  • Microbiology
  • Molecular Biology

Cite this

Xylan degradation, a metabolic property shared by rumen and human colonic Bacteroidetes. / Dodd, Dylan; Mackie, Roderick Ian; Cann, Isaac.

In: Molecular Microbiology, Vol. 79, No. 2, 01.01.2011, p. 292-304.

Research output: Contribution to journalReview article

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