White light diffraction tomography of unlabeled live cells

Tae Woo Kim; S Darin Babacan; Mustafa A. H. Mir; Paul Scott Carney; Lynford L. Goddard; Renjie Zhou; Gabriel Popescu

White light diffraction tomography of unlabeled live cells

Tae Woo Kim (Inventor), S Darin Babacan (Inventor), Mustafa A. H. Mir (Inventor), Paul Scott Carney (Inventor), Lynford L. Goddard (Inventor), Renjie Zhou (Inventor), Gabriel Popescu (Inventor)

Research output: Patent

Abstract

Methods for obtaining a tomographic phase image of a specimen, either in transmission or in scatter. A specimen is illuminated by a temporally incoherent source and light collected in transmission or scattering is used to generate a scattered phase image of the specimen in multiple axial planes. The scattered field is solved for in wavevector space, and a derived instrument function is deconvolved to obtain specimen susceptibility in wavevector space. The specimen susceptibility is transformed to obtain a three-dimensional phase tomogram of the specimen.

Original language	English (US)
U.S. patent number	9404857
Filing date	6/24/14
State	Published - Aug 2 2016

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@misc{d83b1c10f3dd4262a9b58f39112ecf95,

title = "White light diffraction tomography of unlabeled live cells",

abstract = "Methods for obtaining a tomographic phase image of a specimen, either in transmission or in scatter. A specimen is illuminated by a temporally incoherent source and light collected in transmission or scattering is used to generate a scattered phase image of the specimen in multiple axial planes. The scattered field is solved for in wavevector space, and a derived instrument function is deconvolved to obtain specimen susceptibility in wavevector space. The specimen susceptibility is transformed to obtain a three-dimensional phase tomogram of the specimen.",

author = "Kim, {Tae Woo} and Babacan, {S Darin} and Mir, {Mustafa A. H.} and Carney, {Paul Scott} and Goddard, {Lynford L.} and Renjie Zhou and Gabriel Popescu",

year = "2016",

month = aug,

day = "2",

language = "English (US)",

type = "Patent",

note = "9404857",

}

TY - PAT

T1 - White light diffraction tomography of unlabeled live cells

AU - Kim, Tae Woo

AU - Babacan, S Darin

AU - Mir, Mustafa A. H.

AU - Carney, Paul Scott

AU - Goddard, Lynford L.

AU - Zhou, Renjie

AU - Popescu, Gabriel

PY - 2016/8/2

Y1 - 2016/8/2

N2 - Methods for obtaining a tomographic phase image of a specimen, either in transmission or in scatter. A specimen is illuminated by a temporally incoherent source and light collected in transmission or scattering is used to generate a scattered phase image of the specimen in multiple axial planes. The scattered field is solved for in wavevector space, and a derived instrument function is deconvolved to obtain specimen susceptibility in wavevector space. The specimen susceptibility is transformed to obtain a three-dimensional phase tomogram of the specimen.

AB - Methods for obtaining a tomographic phase image of a specimen, either in transmission or in scatter. A specimen is illuminated by a temporally incoherent source and light collected in transmission or scattering is used to generate a scattered phase image of the specimen in multiple axial planes. The scattered field is solved for in wavevector space, and a derived instrument function is deconvolved to obtain specimen susceptibility in wavevector space. The specimen susceptibility is transformed to obtain a three-dimensional phase tomogram of the specimen.

M3 - Patent

M1 - 9404857

Y2 - 2014/06/24

ER -

White light diffraction tomography of unlabeled live cells

Abstract

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