TY - JOUR
T1 - Visualizable detection of nanoscale objects using anti-symmetric excitation and non-resonance amplification
AU - Zhu, Jinlong
AU - Udupa, Aditi
AU - Goddard, Lynford L.
N1 - Funding Information:
This work was funded by Cisco Systems Inc. (Gift Awards CG 1141107 and CG 1377144), University of Illinois at Urbana-Champaign College of Engineering Strategic Research Initiative, and Zhejiang University—University of Illinois at Urbana-Champaign (ZJUI) Institute Research Program. The work was primarily carried out in the Holonyak Micro and Nanotechnology Laboratory, University of Illinois; the final EBL patterning was performed in the Materials Research Laboratory Central Research Facilities, University of Illinois. The authors thank Dr. Edmond Chow and Dr. Tao Shang for performing EBL of the initial and final samples, respectively. The authors gratefully acknowledge Cisco System Inc. for access to its Arcetri cluster. L.L.G. acknowledges the Center for Advanced Study at the University of Illinois for teaching release time.
Publisher Copyright:
© 2020, The Author(s).
PY - 2020/12/1
Y1 - 2020/12/1
N2 - Why can we not see nanoscale objects under a light microscope? The textbook answers are that their relative signals are weak and their separation is smaller than Abbe’s resolution limit. Thus, significant effort has gone into developing ultraviolet imaging, oil and solid immersion objectives, nonlinear methods, fluorescence dyes, evanescent wave tailoring, and point-spread function engineering. In this work, we introduce a new optical sensing framework based on the concepts of electromagnetic canyons and non-resonance amplification, to directly view on a widefield microscope λ/31-scale (25-nm radius) objects in the near-field region of nanowire-based sensors across a 726-μm × 582-μm field of view. Our work provides a simple but highly efficient framework that can transform conventional diffraction-limited optical microscopes for nanoscale visualization. Given the ubiquity of microscopy and importance of visualizing viruses, molecules, nanoparticles, semiconductor defects, and other nanoscale objects, we believe our proposed framework will impact many science and engineering fields.
AB - Why can we not see nanoscale objects under a light microscope? The textbook answers are that their relative signals are weak and their separation is smaller than Abbe’s resolution limit. Thus, significant effort has gone into developing ultraviolet imaging, oil and solid immersion objectives, nonlinear methods, fluorescence dyes, evanescent wave tailoring, and point-spread function engineering. In this work, we introduce a new optical sensing framework based on the concepts of electromagnetic canyons and non-resonance amplification, to directly view on a widefield microscope λ/31-scale (25-nm radius) objects in the near-field region of nanowire-based sensors across a 726-μm × 582-μm field of view. Our work provides a simple but highly efficient framework that can transform conventional diffraction-limited optical microscopes for nanoscale visualization. Given the ubiquity of microscopy and importance of visualizing viruses, molecules, nanoparticles, semiconductor defects, and other nanoscale objects, we believe our proposed framework will impact many science and engineering fields.
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U2 - 10.1038/s41467-020-16610-0
DO - 10.1038/s41467-020-16610-0
M3 - Article
C2 - 32488014
AN - SCOPUS:85085909194
VL - 11
JO - Nature Communications
JF - Nature Communications
SN - 2041-1723
IS - 1
M1 - 2754
ER -