Visible-Light-Induced Dearomatizations

Mikiko Okumura, David Sarlah

Research output: Contribution to journalReview article

Abstract

The dearomatization of aromatic compounds is an important synthetic strategy used in accessing complex three-dimensional structures from simple aromatic precursors. This minireview aims to provide an overview of recent advancements in this area, with a specific focus on visible-light-mediated dearomative transformations. Compared to the conventional high-energy ultraviolet (UV) light-promoted processes, not only these new approaches offer milder reaction conditions to accommodate wider variety of substrates with sensitive functionalities, but also enable the use of photocatalysts and other promoters, significantly expanding the reaction space. Application of these transformations to the synthesis of bioactive compounds are also discussed.

Original languageEnglish (US)
Pages (from-to)1259-1273
Number of pages15
JournalEuropean Journal of Organic Chemistry
Volume2020
Issue number10
DOIs
StatePublished - Mar 15 2020

Keywords

  • Arenes
  • Dearomatization
  • Functionalization
  • Photochemistry
  • Visible light

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Organic Chemistry

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