Virtual evolution of HVEM segment for checkpoint inhibitor discovery

Keyphrases

• Checkpoint Inhibitors 100%
• Herpesvirus Entry Mediator 100%
• Inhibitor Discovery 100%
• Virtual Evolution 100%
• T Cells 80%
• Attenuator 80%
• B Lymphocytes 80%
• Core Sequence 40%
• In Silico 20%
• High Affinity 20%
• Computational Analysis 20%
• In Cancer 20%
• Saturation mutagenesis 20%
• Effective Treatment 20%
• Co-crystal Structure 20%
• Mutation Effect 20%
• Drug Development 20%
• Potent Inhibitor 20%
• Low Binding Energy 20%
• Cancer Research 20%
• Programmed Death-ligand 1 (PD-L1) 20%
• Lab Experiment 20%
• Wet Laboratory 20%
• Immune Checkpoint Molecules 20%
• Immune Therapy 20%

Biochemistry, Genetics and Molecular Biology

• Mediator 100%
• Virus Entry 100%
• Herpesviridae 100%
• T Cell 80%
• B Cell 80%
• Mutagenesis 20%
• Binding Energy 20%
• Immune Checkpoints 20%