Vibrational spectroscopy and imaging for concurrent cellular trafficking of co-localized doxorubicin and deuterated phospholipid vesicles

S. K. Misra; P. Mukherjee; A. Ohoka; A. S. Schwartz-Duval; S. Tiwari; R. Bhargava; D. Pan

doi:10.1039/c5nr07975f

Vibrational spectroscopy and imaging for concurrent cellular trafficking of co-localized doxorubicin and deuterated phospholipid vesicles

S. K. Misra, P. Mukherjee, A. Ohoka, A. S. Schwartz-Duval, S. Tiwari, R. Bhargava, D. Pan

Research output: Contribution to journal › Article › peer-review

Abstract

Simultaneous tracking of nanoparticles and encapsulated payload is of great importance and visualizing their activity is arduous. Here we use vibrational spectroscopy to study the in vitro tracking of co-localized lipid nanoparticles and encapsulated drug employing a model system derived from doxorubicin-encapsulated deuterated phospholipid (dodecyl phosphocholine-d₃₈) single tailed phospholipid vesicles.

Original language	English (US)
Pages (from-to)	2826-2831
Number of pages	6
Journal	Nanoscale
Volume	8
Issue number	5
DOIs	https://doi.org/10.1039/c5nr07975f
State	Published - Feb 7 2016

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Materials Science(all)

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10.1039/c5nr07975f

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abstract = "Simultaneous tracking of nanoparticles and encapsulated payload is of great importance and visualizing their activity is arduous. Here we use vibrational spectroscopy to study the in vitro tracking of co-localized lipid nanoparticles and encapsulated drug employing a model system derived from doxorubicin-encapsulated deuterated phospholipid (dodecyl phosphocholine-d38) single tailed phospholipid vesicles.",

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AU - Ohoka, A.

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AU - Tiwari, S.

AU - Bhargava, R.

AU - Pan, D.

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AB - Simultaneous tracking of nanoparticles and encapsulated payload is of great importance and visualizing their activity is arduous. Here we use vibrational spectroscopy to study the in vitro tracking of co-localized lipid nanoparticles and encapsulated drug employing a model system derived from doxorubicin-encapsulated deuterated phospholipid (dodecyl phosphocholine-d38) single tailed phospholipid vesicles.

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Vibrational spectroscopy and imaging for concurrent cellular trafficking of co-localized doxorubicin and deuterated phospholipid vesicles

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