TY - GEN
T1 - Vascular-targeted imaging using MRI
AU - Li, King C.P.
AU - Bednarski, Mark D.
PY - 2002
Y1 - 2002
N2 - Target specific MRI poses special opportunities and challenges. Although MRI can provide exquisite morphologic details, its relatively low sensitivity has severely hampered the development of target-specific contrast agents that can provide enough signal alteration to be detectable in vivo. In this review, we will present our data on the development of polymerized vesicles for use in vascular-targeted imaging using MRI. Because of the high amount of pay load that can be carried to the target site via these particles, they can be detectable with MRI. In addition, the same platform can be used for delivering multiple different types of contrast ions as well as therapeutic agents to vascular target sites. We believe that by using the same platform for imaging and therapy, we can have an accurate way of personalizing treatment.
AB - Target specific MRI poses special opportunities and challenges. Although MRI can provide exquisite morphologic details, its relatively low sensitivity has severely hampered the development of target-specific contrast agents that can provide enough signal alteration to be detectable in vivo. In this review, we will present our data on the development of polymerized vesicles for use in vascular-targeted imaging using MRI. Because of the high amount of pay load that can be carried to the target site via these particles, they can be detectable with MRI. In addition, the same platform can be used for delivering multiple different types of contrast ions as well as therapeutic agents to vascular target sites. We believe that by using the same platform for imaging and therapy, we can have an accurate way of personalizing treatment.
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U2 - 10.1109/ISBI.2002.1029381
DO - 10.1109/ISBI.2002.1029381
M3 - Conference contribution
AN - SCOPUS:84948696373
T3 - Proceedings - International Symposium on Biomedical Imaging
SP - 809
EP - 810
BT - 2002 IEEE International Symposium on Biomedical Imaging, ISBI 2002 - Proceedings
PB - IEEE Computer Society
T2 - IEEE International Symposium on Biomedical Imaging, ISBI 2002
Y2 - 7 July 2002 through 10 July 2002
ER -