TY - JOUR
T1 - Validity of the Timed Up and Go Test as a Measure of Functional Mobility in Persons with Multiple Sclerosis
AU - Sebastião, Emerson
AU - Sandroff, Brian M.
AU - Learmonth, Yvonne C.
AU - Motl, Robert W.
N1 - Publisher Copyright:
© 2016 American Congress of Rehabilitation Medicine.
PY - 2016/7/1
Y1 - 2016/7/1
N2 - Objective: To examine the validity of the timed Up and Go (TUG) test as a measure of functional mobility in persons with multiple sclerosis (MS) by using a comprehensive framework based on construct validity (ie, convergent and divergent validity). Design: Cross-sectional study. Setting: Hospital setting. Participants: Community-residing persons with MS (N=47). Interventions: Not applicable. Main Outcome Measures: Main outcome measures included the TUG test, timed 25-foot walk test, 6-minute walk test, Multiple Sclerosis Walking Scale-12, Late-Life Function and Disability Instrument, posturography evaluation, Activities-specific Balance Confidence scale, Symbol Digits Modalities Test, Expanded Disability Status Scale, and the number of steps taken per day. Results: The TUG test was strongly associated with other valid outcome measures of ambulatory mobility (Spearman rank correlation, rs=.71-.90) and disability status (rs=.80), moderately to strongly associated with balance confidence (rs=.66), and weakly associated with postural control (ie, balance) (rs=.31). The TUG test was moderately associated with cognitive processing speed (rs=.59), but not associated with other nonambulatory measures (ie, Late-Life Function and Disability Instrument-upper extremity function). Conclusions: Our findings support the validity of the TUG test as a measure of functional mobility. This warrants its inclusion in patients' assessment alongside other valid measures of functional mobility in both clinical and research practice in persons with MS.
AB - Objective: To examine the validity of the timed Up and Go (TUG) test as a measure of functional mobility in persons with multiple sclerosis (MS) by using a comprehensive framework based on construct validity (ie, convergent and divergent validity). Design: Cross-sectional study. Setting: Hospital setting. Participants: Community-residing persons with MS (N=47). Interventions: Not applicable. Main Outcome Measures: Main outcome measures included the TUG test, timed 25-foot walk test, 6-minute walk test, Multiple Sclerosis Walking Scale-12, Late-Life Function and Disability Instrument, posturography evaluation, Activities-specific Balance Confidence scale, Symbol Digits Modalities Test, Expanded Disability Status Scale, and the number of steps taken per day. Results: The TUG test was strongly associated with other valid outcome measures of ambulatory mobility (Spearman rank correlation, rs=.71-.90) and disability status (rs=.80), moderately to strongly associated with balance confidence (rs=.66), and weakly associated with postural control (ie, balance) (rs=.31). The TUG test was moderately associated with cognitive processing speed (rs=.59), but not associated with other nonambulatory measures (ie, Late-Life Function and Disability Instrument-upper extremity function). Conclusions: Our findings support the validity of the TUG test as a measure of functional mobility. This warrants its inclusion in patients' assessment alongside other valid measures of functional mobility in both clinical and research practice in persons with MS.
KW - Mobility limitation
KW - Multiple sclerosis
KW - Rehabilitation
KW - Validation studies
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U2 - 10.1016/j.apmr.2015.12.031
DO - 10.1016/j.apmr.2015.12.031
M3 - Article
AN - SCOPUS:84964663118
VL - 97
SP - 1072
EP - 1077
JO - Archives of Physical Medicine and Rehabilitation
JF - Archives of Physical Medicine and Rehabilitation
SN - 0003-9993
IS - 7
ER -