UV-responsive degradable polymers derived from 1-(4-aminophenyl) ethane-1,2-diol

Liang Ma, Ryan Baumgartner, Yanfeng Zhang, Ziyuan Song, Kaimin Cai, Jianjun Cheng

Research output: Contribution to journalArticlepeer-review


A UV-responsive polymer was prepared via condensation polymerization of 2-nitrobenzyl(4-(1,2-dihydroxyethyl)phenyl)carbamate and azalaic acid dichloride. When the polymer was irradiated with UV light, the nitrobenzyl urethane protecting group was removed and the deprotected aniline underwent spontaneous 1,6-elimination reactions, resulting in degradation of the polymer. Nanoparticles with encapsulated Nile Red were formulated with the degradable polymer and triggered burst release of Nile Red was observed when the nanoparticles were irradiated by UV light.

Original languageEnglish (US)
Pages (from-to)1161-1168
Number of pages8
JournalJournal of Polymer Science, Part A: Polymer Chemistry
Issue number9
StatePublished - May 1 2015


  • degradable materials
  • depolymerization
  • nanoparticles
  • photochemistry
  • polyester
  • self immolative
  • stimuli-sensitive polymer
  • triggered release

ASJC Scopus subject areas

  • Polymers and Plastics
  • Organic Chemistry
  • Materials Chemistry


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