Unleashing the power of energy storage: Engineering β-oxidation pathways for polyketide production

Bin Wang, Huimin Zhao

Research output: Contribution to journalComment/debate

Abstract

Overproduction of polyketides has been a challenge for metabolic engineering for decades. However, recent studies have demonstrated that in both native host and heterologous host, engineering β -oxidation pathways can lead to dramatic improvement of polyketide production.

Original languageEnglish (US)
Pages (from-to)21-22
Number of pages2
JournalSynthetic and Systems Biotechnology
Volume5
Issue number1
DOIs
StatePublished - Mar 2020

Keywords

  • Beta-oxidation pathway
  • Metabolic engineering
  • Polyketide
  • Triacylglycerols

ASJC Scopus subject areas

  • Structural Biology
  • Biomedical Engineering
  • Applied Microbiology and Biotechnology
  • Genetics

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