Ultrasound and photoacoustic image-guided photothermal therapy using silica-coated gold nanorods: In-vivo study

Seungsoo Kim, Yun Sheng Chen, Geoffrey P. Luke, Mohammad Mehrmohammadi, Jason R. Cook, Stanislav Y. Emelianov

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In nanoparticle mediated photothermal therapy, confirmation of nanoparticle delivery/deposition in a tumor before therapy and temperature monitoring during therapy are needed to optimize therapeutic outcomes. In this paper, we demonstrate that ultrasound and photoacoustic imaging techniques can plan and guide photothermal cancer therapy, using an in-vivo mouse model of subcutaneous cancer intravenously administrated with silica-coated gold nanorods.

Original languageEnglish (US)
Title of host publication2010 IEEE International Ultrasonics Symposium, IUS 2010
Pages233-236
Number of pages4
DOIs
StatePublished - Dec 1 2010
Externally publishedYes
Event2010 IEEE International Ultrasonics Symposium, IUS 2010 - San Diego, CA, United States
Duration: Oct 11 2010Oct 14 2010

Publication series

NameProceedings - IEEE Ultrasonics Symposium
ISSN (Print)1051-0117

Other

Other2010 IEEE International Ultrasonics Symposium, IUS 2010
CountryUnited States
CitySan Diego, CA
Period10/11/1010/14/10

Keywords

  • Nanoparticles
  • photoacoustics
  • photothermal therapy
  • spectroscopy
  • thermal imaging

ASJC Scopus subject areas

  • Acoustics and Ultrasonics

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