Abstract

This chapter summarizes the approaches to tissue elasticity imaging based on ultrasonic and/or optical modalities that have been developed during the last three decades. We describe a wide range of techniques, from simply mapping soft-tissue stiffness to accurately estimating a complex modulus of viscoelastic tissues, in vivo. We describe how experimental parameters determine the spatiotemporal properties of the force that then couple to the properties of the imaging system used to track deformations and to specific tissue geometries. These experimental-design parameters determine the resolution and noise properties of the image, and they can also be set to select which elements of tissue structure contribute to the object contrast. Parameter selection depends on measurement goals, which might include anything from a basic-science investigation into mechanobiology of disease processes to diagnosis of focal diseases in a patient. Although there are many coupled parameters to consider, they provide a broad pallet of opportunities for discovery and diagnosis related to changes in the mechanical properties of tissues.

Original languageEnglish (US)
Title of host publicationHandbook of Imaging in Biological Mechanics
PublisherCRC Press
Pages83-96
Number of pages14
ISBN (Electronic)9781466588141
ISBN (Print)9781466588134
DOIs
StatePublished - Jan 1 2014

Fingerprint

Ultrasonics
optics
Tissue
Imaging techniques
Biophysics
Elasticity Imaging Techniques
Pallets
Noise
Research Design
Imaging systems
Design of experiments
Elasticity
stiffness
estimating
elastic properties
ultrasonics
Stiffness
mechanical properties
Mechanical properties
Geometry

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Engineering(all)
  • Physics and Astronomy(all)

Cite this

Wang, Y., Adie, S. G., Boppart, S. A., & Insana, M. (2014). Ultrasound and optical methods for dynamic viscoelastic imaging. In Handbook of Imaging in Biological Mechanics (pp. 83-96). CRC Press. https://doi.org/10.1201/b17566

Ultrasound and optical methods for dynamic viscoelastic imaging. / Wang, Yue; Adie, Steven G.; Boppart, Stephen Allen; Insana, Michael.

Handbook of Imaging in Biological Mechanics. CRC Press, 2014. p. 83-96.

Research output: Chapter in Book/Report/Conference proceedingChapter

Wang, Y, Adie, SG, Boppart, SA & Insana, M 2014, Ultrasound and optical methods for dynamic viscoelastic imaging. in Handbook of Imaging in Biological Mechanics. CRC Press, pp. 83-96. https://doi.org/10.1201/b17566
Wang Y, Adie SG, Boppart SA, Insana M. Ultrasound and optical methods for dynamic viscoelastic imaging. In Handbook of Imaging in Biological Mechanics. CRC Press. 2014. p. 83-96 https://doi.org/10.1201/b17566
Wang, Yue ; Adie, Steven G. ; Boppart, Stephen Allen ; Insana, Michael. / Ultrasound and optical methods for dynamic viscoelastic imaging. Handbook of Imaging in Biological Mechanics. CRC Press, 2014. pp. 83-96
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