Ultrasonic mechanical relaxation imaging and the material science of breast cancer

Michael F. Insana, Liu Jie, Mallika Sridhar, Claire Pellot-Barakat

Research output: Chapter in Book/Report/Conference proceedingConference contribution


A time series of strain images is acquired while applying a ramp-and-hold compression to measure viscous creep from which viscoelastic properties of breast stroma can be measured. The literature on the ultrastructure of breast connective tissue suggests that profound changes occur during tumor formation that may generate contrast for viscoelastic properties. We review the continuum mechanics of uniaxial compressions of hydrated polymers to develop the feature space for our imaging approach. Two examples of clinical breast images show classic sonographic and elastographic features, and also suggest that viscoelastic properties, particularly the first strain retardance time constant T1, may provide unique diagnostic opportunities.

Original languageEnglish (US)
Title of host publication2005 IEEE Ultrasonics Symposium
Number of pages4
StatePublished - 2005
Event2005 IEEE Ultrasonics Symposium - Rotterdam, Netherlands
Duration: Sep 18 2005Sep 21 2005

Publication series

NameProceedings - IEEE Ultrasonics Symposium
ISSN (Print)1051-0117


Other2005 IEEE Ultrasonics Symposium

ASJC Scopus subject areas

  • Acoustics and Ultrasonics


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