Ultrasonic backscatter coefficients for weakly scattering, agar spheres in agar phantoms

Michael R. King; Janelle J. Anderson; Maria Teresa Herd; Darryl Ma; Alexander Haak; Lauren A. Wirtzfeld; Ernest L. Madsen; James A. Zagzebski; Michael L. Oelze; Timothy J. Hall; William D. O'Brien

doi:10.1121/1.3460109

Ultrasonic backscatter coefficients for weakly scattering, agar spheres in agar phantoms

Michael R. King, Janelle J. Anderson, Maria Teresa Herd, Darryl Ma, Alexander Haak, Lauren A. Wirtzfeld, Ernest L. Madsen, James A. Zagzebski, Michael L. Oelze, Timothy J. Hall, William D. O'Brien

Research output: Contribution to journal › Article › peer-review

Abstract

Applicability of ultrasound phantoms to biological tissue has been limited because most phantoms have generally used strong scatterers. The objective was to develop very weakly scattering phantoms, whose acoustic scattering properties are likely closer to those of tissues and then compare theoretical simulations and experimental backscatter coefficient (BSC) results. The phantoms consisted of agar spheres of various diameters (nominally between 90 and 212 μm), containing ultrafiltered milk, suspended in an agar background. BSC estimates were performed at two institutions over the frequency range 1-13 MHz, and compared to three models. Excellent agreement was shown between the two laboratory results as well as with the three models.

Original language	English (US)
Pages (from-to)	903-908
Number of pages	6
Journal	Journal of the Acoustical Society of America
Volume	128
Issue number	2
DOIs	https://doi.org/10.1121/1.3460109
State	Published - Aug 2010
Externally published	Yes

ASJC Scopus subject areas

Arts and Humanities (miscellaneous)
Acoustics and Ultrasonics

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10.1121/1.3460109

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title = "Ultrasonic backscatter coefficients for weakly scattering, agar spheres in agar phantoms",

abstract = "Applicability of ultrasound phantoms to biological tissue has been limited because most phantoms have generally used strong scatterers. The objective was to develop very weakly scattering phantoms, whose acoustic scattering properties are likely closer to those of tissues and then compare theoretical simulations and experimental backscatter coefficient (BSC) results. The phantoms consisted of agar spheres of various diameters (nominally between 90 and 212 μm), containing ultrafiltered milk, suspended in an agar background. BSC estimates were performed at two institutions over the frequency range 1-13 MHz, and compared to three models. Excellent agreement was shown between the two laboratory results as well as with the three models.",

author = "King, {Michael R.} and Anderson, {Janelle J.} and Herd, {Maria Teresa} and Darryl Ma and Alexander Haak and Wirtzfeld, {Lauren A.} and Madsen, {Ernest L.} and Zagzebski, {James A.} and Oelze, {Michael L.} and Hall, {Timothy J.} and O'Brien, {William D.}",

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AU - King, Michael R.

AU - Anderson, Janelle J.

AU - Herd, Maria Teresa

AU - Ma, Darryl

AU - Haak, Alexander

AU - Wirtzfeld, Lauren A.

AU - Madsen, Ernest L.

AU - Zagzebski, James A.

AU - Oelze, Michael L.

AU - Hall, Timothy J.

AU - O'Brien, William D.

N1 - Funding Information: This work is supported by NIH Grant CA111289, a BRP between the University of Illinois at Urbana-Champaign and University of Wisconsin-Madison.

PY - 2010/8

Y1 - 2010/8

N2 - Applicability of ultrasound phantoms to biological tissue has been limited because most phantoms have generally used strong scatterers. The objective was to develop very weakly scattering phantoms, whose acoustic scattering properties are likely closer to those of tissues and then compare theoretical simulations and experimental backscatter coefficient (BSC) results. The phantoms consisted of agar spheres of various diameters (nominally between 90 and 212 μm), containing ultrafiltered milk, suspended in an agar background. BSC estimates were performed at two institutions over the frequency range 1-13 MHz, and compared to three models. Excellent agreement was shown between the two laboratory results as well as with the three models.

AB - Applicability of ultrasound phantoms to biological tissue has been limited because most phantoms have generally used strong scatterers. The objective was to develop very weakly scattering phantoms, whose acoustic scattering properties are likely closer to those of tissues and then compare theoretical simulations and experimental backscatter coefficient (BSC) results. The phantoms consisted of agar spheres of various diameters (nominally between 90 and 212 μm), containing ultrafiltered milk, suspended in an agar background. BSC estimates were performed at two institutions over the frequency range 1-13 MHz, and compared to three models. Excellent agreement was shown between the two laboratory results as well as with the three models.

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Ultrasonic backscatter coefficients for weakly scattering, agar spheres in agar phantoms

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