Ultrasonic and elasticity imaging to model disease-induced changes in soft-tissue structure

Pawan Chaturvedi, Michael F. Insana, Timothy J. Hall

Research output: Contribution to journalArticlepeer-review


Ultrasonic techniques are presented for the study of soft biological tissue structure and function. Changes in echo waveforms caused by microscopic variations in the mechanical properties of tissue can reveal disease mechanism, in vivo. On a larger scale, elasticity imaging describes the macroscopic mechanical properties of soft tissues. We summarize the approach and present preliminary results for studying disease-induced changes in renal tissue using these two acoustic imaging techniques.

Original languageEnglish (US)
Pages (from-to)325-338
Number of pages14
JournalMedical Image Analysis
Issue number4
StatePublished - 1998
Externally publishedYes


  • Elasticity
  • Elastography
  • Microstructure
  • Renal disease
  • Soft-tissue disease
  • Strain imaging
  • Ultrasonic imaging
  • Ultrasound

ASJC Scopus subject areas

  • Computer Graphics and Computer-Aided Design
  • Computer Vision and Pattern Recognition
  • Biomedical Engineering
  • Radiology Nuclear Medicine and imaging
  • Medicine (miscellaneous)
  • Computer Science (miscellaneous)


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