We present tunable image-mapping optical coherence tomography (TIM-OCT), which can provide optimized imaging performance for a given application by using a programmable phase-only spatial light modulator in a low-coherence full-field spectral-domain interferometer. The resultant system can provide either a high lateral resolution or a high axial resolution in a snapshot without moving parts. Alternatively, the system can achieve a high resolution along all dimensions through a multiple-shot acquisition. We evaluated TIM-OCT in imaging both standard targets and biological samples. Additionally, we demonstrated the integration of TIM-OCT with computational adaptive optics in correcting sample-induced optical aberrations.

Original languageEnglish (US)
Pages (from-to)627-638
Number of pages12
JournalBiomedical Optics Express
Issue number2
StatePublished - Feb 1 2023

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Biotechnology


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