Tunability of liquid-infused silicone materials for biointerfaces

Irini Sotiri, Amanda Tajik, Yang Lai, Cathy T. Zhang, Yevgen Kovalenko, Carine R. Nemr, Haylea Ledoux, Jack Alvarenga, Edythe Johnson, Huseini S. Patanwala, Jaakko V.I. Timonen, Yuhang Hu, Joanna Aizenberg, Caitlin Howell

Research output: Contribution to journalArticlepeer-review

Abstract

The ability to control the properties of bio-inspired liquid-infused surfaces is of interest in a wide range of applications. Liquid layers created using oil-infused polydimethylsiloxane elastomers offer a potentially simple way of accomplishing this goal through the adjustment of parameters such as curing agent ratio and oil viscosity. In this work, the effect of tuning these compositional parameters on the properties of the infused polymer are investigated, including infusion dynamics, stiffness, longevity in the face of continuous liquid overlayer removal, and resistance to bacterial adhesion. It is found that that curing agent concentration appears to have the greatest impact on the functionality of the system, with a lower base-to-curing agent ratio resulting in both increased longevity and improved resistance to adhesion by Escherichia coli. A demonstration of how these findings may be implemented to introduce patterned wettability to the surface of the infused polymers is presented by controlling the spatial arrangement of bacteria. These results demonstrate a new degree of control over immobilized liquid layers and will facilitate their use in future applications.

Original languageEnglish (US)
Article number06D401
JournalBiointerphases
Volume13
Issue number6
DOIs
StatePublished - Dec 1 2018
Externally publishedYes

ASJC Scopus subject areas

  • Chemistry(all)
  • Biomaterials
  • Materials Science(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Physics and Astronomy(all)

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