Translation, cultural adaptation, and validation of the celiac disease DUX (CDDUX)

Manuela Torres Camara Lins, Rafael Miranda Tassitano, Kátia Galeão Brandt, Margarida Maria De Castro Antunes, Giselia Alves Pontes Da Silva

Research output: Contribution to journalArticlepeer-review


Objective To translate, cross-culturally adapt, and validate a specific questionnaire for the evaluation of celiac children and adolescents, the celiac disease DUX (CDDUX). Methods The steps suggested by Reichenheim and Moraes (2007) were followed to obtain conceptual, item, semantic, operational, and measurement equivalences. Four pediatric gastroenterologists; a researcher with tool validation background; three English teachers; and 33 celiac patients, aged 8-18 years, and their caregivers participated in the study. The scores of celiac patients and those obtained from their caregivers were compared. Among the patients, the scores were compared in relation to gender and age. Results All items were considered relevant to the construct and good semantic equivalence of the version was acquired. During measurement equivalence, the exploratory factor analysis showed appropriate weight of all items and good internal consistency, with Cronbach's α of 0.81. Significant difference was found among the final scores of children and their caregivers. There was no difference among the final scores in relation to gender or age. Conclusion The questionnaire was translated and adapted according to all the proposed steps, with all equivalences adequately met. It is a valid tool to access the QoL of celiac children and adolescents in the translated language.

Original languageEnglish (US)
Pages (from-to)448-454
Number of pages7
JournalJornal de Pediatria
Issue number5
StatePublished - Sep 1 2015
Externally publishedYes


  • Celiac disease
  • Cross-cultural adaptation
  • Quality of life

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


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