Transgenic animals in biomedicine and agriculture: Outlook for the future

M. B. Wheeler, E. M. Walters, S. G. Clark

Research output: Contribution to journalArticlepeer-review

Abstract

Transgenic animals are produced by introduction of 'foreign' deoxyribonucleic acid (DNA) into preimplantation embryos. The foreign DNA is inserted into the genetic material and may be expressed in tissues of the resulting individual. This technique is of great importance to many aspects of biomedical science including gene regulation, the immune system, cancer research, developmental biology, biomedicine, manufacturing and agriculture. The production of transgenic animals is one of a number of new and developing technologies that will have a profound impact on the genetic improvement of livestock. The rate at which these technologies are incorporated into production schemes will determine the speed at which we will be able to achieve our goal of more efficiently producing livestock, which meets consumer and market demand.

Original languageEnglish (US)
Pages (from-to)265-289
Number of pages25
JournalAnimal reproduction science
Volume79
Issue number3-4
DOIs
StatePublished - Dec 15 2003

Keywords

  • Biomedicine
  • Embryonic stem cells
  • Knock-outs
  • Microinjection
  • Nuclear transfer
  • Transgenic

ASJC Scopus subject areas

  • Animal Science and Zoology
  • Biotechnology
  • Genetics

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