Tracking progressive renal disease with quantitative ultrasonic imaging

Timothy J. Hall, Pawan Chaturvedi, Michael F. Insana, John G. Wood, Htet Khant, Yanning Zhu, David Preston, Benjamin D. Cowley

Research output: Contribution to journalConference articlepeer-review


The progression of polycystic kidney disease (PKD) to renal failure was studied in a rat model. The experiment involved the use of ultrasound to noninvasively detect morphological changes early in the disease process when interventions are most successful and before there is a significant loss in renal function. Preliminary results suggest that microstructural changes due to PKD are disrupting the tissue macrostructure at a very early stage of the disease. The combined results suggest the quantitative ultrasonic imaging (QUS) may have a significant role in diagnosing and tracking renal disease progression.

Original languageEnglish (US)
Pages (from-to)1341-1344
Number of pages4
JournalProceedings of the IEEE Ultrasonics Symposium
StatePublished - 1998
Externally publishedYes
EventProceedings of the 1998 International Ultrasonics Symposium - Sendai, Miyagi, Jpn
Duration: Oct 5 1998Oct 8 1998

ASJC Scopus subject areas

  • Acoustics and Ultrasonics


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