TY - GEN
T1 - Towards interactive visualization for exploring conserved motifs in noncoding DNA sequence
AU - Congdon, Clare Bates
AU - Gaskins, H Rex
AU - Nava, Gerardo M.
AU - Mattingly, Carolyn
PY - 2007
Y1 - 2007
N2 - Computational inference of putative functional elements in noncoding DNA sequence can significantly hasten the search for verified functional elements, such as transcription factor binding sites. However, while computational methods are able to identify promising putative elements, the number of regions of interest may remain unrealistic for experimental validation. Visualization of putative functional elements can assist tremendously in identifying the regions of greatest interest; interactive vizualization allows researchers additional means of asking and answering questions about putative elements. For example, interactive visualizations allow one to look at motifs in the context of verified functional elements or other putative elements, interactively altering the amount of information displayed and the level of resolution at which it is displayed. The work presented here describes initial efforts toward interactive visualization of putative junctional elements specifically for our work with conserved elements.
AB - Computational inference of putative functional elements in noncoding DNA sequence can significantly hasten the search for verified functional elements, such as transcription factor binding sites. However, while computational methods are able to identify promising putative elements, the number of regions of interest may remain unrealistic for experimental validation. Visualization of putative functional elements can assist tremendously in identifying the regions of greatest interest; interactive vizualization allows researchers additional means of asking and answering questions about putative elements. For example, interactive visualizations allow one to look at motifs in the context of verified functional elements or other putative elements, interactively altering the amount of information displayed and the level of resolution at which it is displayed. The work presented here describes initial efforts toward interactive visualization of putative junctional elements specifically for our work with conserved elements.
UR - http://www.scopus.com/inward/record.url?scp=49349090523&partnerID=8YFLogxK
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U2 - 10.1109/FBIT.2007.149
DO - 10.1109/FBIT.2007.149
M3 - Conference contribution
AN - SCOPUS:49349090523
SN - 0769529992
SN - 9780769529998
T3 - Proceedings of the Frontiers in the Convergence of Bioscience and Information Technologies, FBIT 2007
SP - 234
EP - 237
BT - Proceedings of the Frontiers in the Convergence of Bioscience and Information Technologies, FBIT 2007
T2 - Frontiers in the Convergence of Bioscience and Information Technologies, FBIT 2007
Y2 - 11 October 2007 through 13 October 2007
ER -