Towards a foundational representation of potential drug-drug interaction knowledge

Mathias Brochhausen; Jodi Schneider; Daniel Malone; Philip E. Empey; William R. Hogan; Richard D. Boyce

Towards a foundational representation of potential drug-drug interaction knowledge

Mathias Brochhausen, Jodi Schneider, Daniel Malone, Philip E. Empey, William R. Hogan, Richard D. Boyce

Research output: Contribution to journal › Conference article › peer-review

Abstract

Inadequate representation of evidence and knowledge about potential drug-drug interactions is a major factor underlying disagreements among sources of drug information that are used by clinicians. In this paper we describe the initial steps toward developing a foundational domain representation that allows tracing the evidence underlying potential drug-drug interaction knowledge. The new representation includes biological and biomedical entities represented in existing ontologies and terminologies to foster integration of data from relevant fields such as physiology, anatomy, and laboratory sciences.

Original language	English (US)
Pages (from-to)	16-31
Number of pages	16
Journal	CEUR Workshop Proceedings
Volume	1309
State	Published - 2014
Externally published	Yes
Event	Joint ICBO-WS 2014 1st International Workshop on Drug Interaction Knowledge Management, DIKR 2014, the 2nd International Workshop on Definitions in Ontologies, IWOOD 2014, and the Starting an OBI-Based Biobank Ontology Workshop, OBIB 2014 - Co-located with the International Conference on Biomedical Ontologies, ICBO 2014 - Houston, United States Duration: Oct 6 2014 → Oct 9 2014

Keywords

Knowledge management
Ontologies
Potential drug-drug interactions

ASJC Scopus subject areas

General Computer Science

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abstract = "Inadequate representation of evidence and knowledge about potential drug-drug interactions is a major factor underlying disagreements among sources of drug information that are used by clinicians. In this paper we describe the initial steps toward developing a foundational domain representation that allows tracing the evidence underlying potential drug-drug interaction knowledge. The new representation includes biological and biomedical entities represented in existing ontologies and terminologies to foster integration of data from relevant fields such as physiology, anatomy, and laboratory sciences.",

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AU - Brochhausen, Mathias

AU - Schneider, Jodi

AU - Malone, Daniel

AU - Empey, Philip E.

AU - Hogan, William R.

AU - Boyce, Richard D.

PY - 2014

Y1 - 2014

N2 - Inadequate representation of evidence and knowledge about potential drug-drug interactions is a major factor underlying disagreements among sources of drug information that are used by clinicians. In this paper we describe the initial steps toward developing a foundational domain representation that allows tracing the evidence underlying potential drug-drug interaction knowledge. The new representation includes biological and biomedical entities represented in existing ontologies and terminologies to foster integration of data from relevant fields such as physiology, anatomy, and laboratory sciences.

AB - Inadequate representation of evidence and knowledge about potential drug-drug interactions is a major factor underlying disagreements among sources of drug information that are used by clinicians. In this paper we describe the initial steps toward developing a foundational domain representation that allows tracing the evidence underlying potential drug-drug interaction knowledge. The new representation includes biological and biomedical entities represented in existing ontologies and terminologies to foster integration of data from relevant fields such as physiology, anatomy, and laboratory sciences.

KW - Knowledge management

KW - Ontologies

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M3 - Conference article

AN - SCOPUS:84925615446

SN - 1613-0073

VL - 1309

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JO - CEUR Workshop Proceedings

JF - CEUR Workshop Proceedings

T2 - Joint ICBO-WS 2014 1st International Workshop on Drug Interaction Knowledge Management, DIKR 2014, the 2nd International Workshop on Definitions in Ontologies, IWOOD 2014, and the Starting an OBI-Based Biobank Ontology Workshop, OBIB 2014 - Co-located with the International Conference on Biomedical Ontologies, ICBO 2014

Y2 - 6 October 2014 through 9 October 2014

ER -

Towards a foundational representation of potential drug-drug interaction knowledge

Abstract

Keywords

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