Total synthesis of hirsutellone B

K. C. Nicolaou; David Sarlah; T. Robert Wu; Weiqiang Zhan

doi:10.1002/anie.200903382

Total synthesis of hirsutellone B

K. C. Nicolaou, David Sarlah, T. Robert Wu, Weiqiang Zhan

Research output: Contribution to journal › Article › peer-review

Abstract

Cascading reactions, including the conversion of a TMSepoxy tetraene 1 into the hirsutellone tricyclic core 2, feature heavily in the first total synthesis of the antituberculosis fungal metabolite hirsutellone B. TMS=trimethylsilyl, LA=Lewis acid.

Original language	English (US)
Pages (from-to)	6870-6874
Number of pages	5
Journal	Angewandte Chemie - International Edition
Volume	48
Issue number	37
DOIs	https://doi.org/10.1002/anie.200903382
State	Published - Sep 1 2009
Externally published	Yes

Keywords

Antituberculosis
Cascade reactions
Natural product
Total synthesis

ASJC Scopus subject areas

Catalysis
Chemistry(all)

Online availability

10.1002/anie.200903382

Library availability

Discover UIUC Full Text

Cite this

@article{eb029462582f4c8193aec3486410c7ee,

title = "Total synthesis of hirsutellone B",

abstract = "Cascading reactions, including the conversion of a TMSepoxy tetraene 1 into the hirsutellone tricyclic core 2, feature heavily in the first total synthesis of the antituberculosis fungal metabolite hirsutellone B. TMS=trimethylsilyl, LA=Lewis acid.",

keywords = "Antituberculosis, Cascade reactions, Natural product, Total synthesis",

author = "Nicolaou, {K. C.} and David Sarlah and {Robert Wu}, T. and Weiqiang Zhan",

year = "2009",

month = sep,

day = "1",

doi = "10.1002/anie.200903382",

language = "English (US)",

volume = "48",

pages = "6870--6874",

journal = "Angewandte Chemie - International Edition",

issn = "1433-7851",

publisher = "John Wiley & Sons, Ltd.",

number = "37",

}

TY - JOUR

T1 - Total synthesis of hirsutellone B

AU - Nicolaou, K. C.

AU - Sarlah, David

AU - Robert Wu, T.

AU - Zhan, Weiqiang

PY - 2009/9/1

Y1 - 2009/9/1

N2 - Cascading reactions, including the conversion of a TMSepoxy tetraene 1 into the hirsutellone tricyclic core 2, feature heavily in the first total synthesis of the antituberculosis fungal metabolite hirsutellone B. TMS=trimethylsilyl, LA=Lewis acid.

AB - Cascading reactions, including the conversion of a TMSepoxy tetraene 1 into the hirsutellone tricyclic core 2, feature heavily in the first total synthesis of the antituberculosis fungal metabolite hirsutellone B. TMS=trimethylsilyl, LA=Lewis acid.

KW - Antituberculosis

KW - Cascade reactions

KW - Natural product

KW - Total synthesis

UR - http://www.scopus.com/inward/record.url?scp=69549126522&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=69549126522&partnerID=8YFLogxK

U2 - 10.1002/anie.200903382

DO - 10.1002/anie.200903382

M3 - Article

C2 - 19685548

AN - SCOPUS:69549126522

SN - 1433-7851

VL - 48

SP - 6870

EP - 6874

JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

IS - 37

ER -

Total synthesis of hirsutellone B

Abstract

Keywords

ASJC Scopus subject areas

Online availability

Library availability

Related links

Fingerprint

Cite this