@inproceedings{ac1b12da4c564c3bbba8aa7cd5291847,
title = "Total internal reflection fluorescence of molecular beacons in a multiplexed microfluidic device",
abstract = "Molecular beacons can be used as an ultra-sensitive means of DNA detection, with discrimination capability down to a single base pair mismatch. Assays that utilize these beacons are often performed in 96- or 386-well microplates. To vastly increase the benefits of molecular beacon technology, we present here a combinatorial microfluidic network with surface-tethered molecular beacons for highly sensitive identification of oligomer targets. Total internal reflection fluorescence microscopy (TIRF-M) is used for characterization of binding events in a multiplexed microfluidic array of sub-nanoliter wells.",
keywords = "Molecular beacons, Multiplexing, TIRF, Virus identification",
author = "Schudel, {Benjamin R.} and Melikhan Tanyeri and Schroeder, {Charles M.} and Kenis, {Paul J.A.}",
year = "2009",
language = "English (US)",
isbn = "9780979806421",
series = "Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences",
publisher = "Chemical and Biological Microsystems Society",
pages = "36--38",
booktitle = "Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences",
note = "13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2009 ; Conference date: 01-11-2009 Through 05-11-2009",
}