Thermochemical nanolithography of multifunctional nanotemplates for assembling nano-objects

Debin Wang, Vamsi K. Kodali, William D. Underwood, Jonas E. Jarvholm, Takashi Okada, Simon C. Jones, Mariacristina Rumi, Zhenting Dai, William P. King, Seth R. Marder, Jennifer E. Curtis, Elisa Riedo

Research output: Contribution to journalArticlepeer-review


Nanoscale chemical patterning of different chemical species (amine, thiol, aldehyde, and biotin) in independent nanopatterns is achieved by the iterative application of thermochemicai nanolithography (TCNL) to inscribe amine patterns followed by their chemical conversion to other functional groups. Due to the unique chemical stability of the patterns, the resultant substrates can be stored for weeks and subsequently be used for covalent and molecularrecognition- based attachment of nano-objects using standard chemical protocols. In particular, the ability of this method to attach proteins and DNA to the chemical nanopatterns and to create co-patterns of two distinctive bioactive proteins is demonstrated.

Original languageEnglish (US)
Pages (from-to)3696-3702
Number of pages7
JournalAdvanced Functional Materials
Issue number23
StatePublished - Sep 12 2009

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • General Chemistry
  • Condensed Matter Physics
  • General Materials Science
  • Electrochemistry
  • Biomaterials


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