Thermo-structural studies of spores subjected to high temperature gas environments

Rakesh Kumar, Samarth Saurav, E. V. Titov, D. A. Levin, R. F. Long, W. C. Neely, Peter Setlow

Research output: Contribution to journalArticlepeer-review

Abstract

One of the major mechanisms of deactivating spores is to expose them to elevated temperatures. Experiments carried out in an exposure tube to study the effects on spores in a high temperature gas environment provide evidence of spore deactivation, although the deactivation mechanism is not clear. Numerical studies have been performed to complement the experimental work and to study the effects of various parameters, such as gas temperature, exposure time, and internal pressure on spore survivability. The laminar and turbulent flow fields of a sudden expansion inside the thermal exposure system were simulated by computational fluid dynamics. A thermo-structural model with wall porosity was developed to take into account the dynamic response of the spore wall structure to the internal pressure exerted by the heated vapor on the spore wall. Finally, the results of the transient heat transfer and the thermo-structural models are discussed in the context of the uncertainties in biological system parameters and spore survivability.

Original languageEnglish (US)
Pages (from-to)755-765
Number of pages11
JournalInternational Journal of Heat and Mass Transfer
Volume54
Issue number4
DOIs
StatePublished - Jan 31 2011
Externally publishedYes

Keywords

  • CFD analysis
  • Spore survivability
  • Thermo-structural model

ASJC Scopus subject areas

  • Condensed Matter Physics
  • Mechanical Engineering
  • Fluid Flow and Transfer Processes

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