Abstract
Gain ranging is incorporated into the data acquisition and processing protocol for a Fourier transform infrared (FT-IR) imaging spectrometer employing a focal plane array (FPA) detector. A model for predicting the signal, noise, and signal-to-noise ratio (SNR) for an FPA in terms of the dynamic range of the analog-to-digital converter (ADC) is presented. Conventional gain ranging theory, modified to account for variation of noise with gain by incorporating a linear model for noise prediction, is shown to provide excellent agreement with observed values for the SNR advantage afforded by gain ranging. SNR improvement, as affected by collection parameters, was shown to be limited by the noise characteristics of the FPA detector. The advantages of gain ranging were demonstrated by spectroscopic imaging of a thin section of human prostate tissue.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1580-1589 |
| Number of pages | 10 |
| Journal | Applied Spectroscopy |
| Volume | 55 |
| Issue number | 12 |
| DOIs | |
| State | Published - Dec 1 2001 |
| Externally published | Yes |
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Keywords
- Carcinoma
- FT-IR
- Gain ranging
- Imaging: Hyperspectral
- Noise
- Prostate
- Quantitative
- Signal
- Signal-to-noise ratio
- Spectroscopy
- Step-scan
ASJC Scopus subject areas
- Spectroscopy
- Instrumentation
Cite this
Theory and application of gain ranging to Fourier transform infrared spectroscopic imaging. / Bhargava, Rohit; Fernandez, Daniel C.; Schaeberle, Michael D.; Levin, Ira W.
In: Applied Spectroscopy, Vol. 55, No. 12, 01.12.2001, p. 1580-1589.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Theory and application of gain ranging to Fourier transform infrared spectroscopic imaging
AU - Bhargava, Rohit
AU - Fernandez, Daniel C.
AU - Schaeberle, Michael D.
AU - Levin, Ira W.
PY - 2001/12/1
Y1 - 2001/12/1
N2 - Gain ranging is incorporated into the data acquisition and processing protocol for a Fourier transform infrared (FT-IR) imaging spectrometer employing a focal plane array (FPA) detector. A model for predicting the signal, noise, and signal-to-noise ratio (SNR) for an FPA in terms of the dynamic range of the analog-to-digital converter (ADC) is presented. Conventional gain ranging theory, modified to account for variation of noise with gain by incorporating a linear model for noise prediction, is shown to provide excellent agreement with observed values for the SNR advantage afforded by gain ranging. SNR improvement, as affected by collection parameters, was shown to be limited by the noise characteristics of the FPA detector. The advantages of gain ranging were demonstrated by spectroscopic imaging of a thin section of human prostate tissue.
AB - Gain ranging is incorporated into the data acquisition and processing protocol for a Fourier transform infrared (FT-IR) imaging spectrometer employing a focal plane array (FPA) detector. A model for predicting the signal, noise, and signal-to-noise ratio (SNR) for an FPA in terms of the dynamic range of the analog-to-digital converter (ADC) is presented. Conventional gain ranging theory, modified to account for variation of noise with gain by incorporating a linear model for noise prediction, is shown to provide excellent agreement with observed values for the SNR advantage afforded by gain ranging. SNR improvement, as affected by collection parameters, was shown to be limited by the noise characteristics of the FPA detector. The advantages of gain ranging were demonstrated by spectroscopic imaging of a thin section of human prostate tissue.
KW - Carcinoma
KW - FT-IR
KW - Gain ranging
KW - Imaging: Hyperspectral
KW - Noise
KW - Prostate
KW - Quantitative
KW - Signal
KW - Signal-to-noise ratio
KW - Spectroscopy
KW - Step-scan
UR - http://www.scopus.com/inward/record.url?scp=0035697525&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0035697525&partnerID=8YFLogxK
U2 - 10.1366/0003702011954143
DO - 10.1366/0003702011954143
M3 - Article
AN - SCOPUS:0035697525
VL - 55
SP - 1580
EP - 1589
JO - Applied Spectroscopy
JF - Applied Spectroscopy
SN - 0003-7028
IS - 12
ER -