Abstract
We measured cytoskeletal prestress and stiffness in cultured airway smooth muscle cells treated with graded doses of histamine and isoproterenol, and with colchicine. The stiffness increased in proportion with increasing prestress. This feature is the hallmark of systems known as stress-supported structures. In addition, microtubules balanced a substantial, but relatively small fraction of the prestress.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1466-1467 |
| Number of pages | 2 |
| Journal | Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings |
| Volume | 2 |
| State | Published - 2002 |
| Externally published | Yes |
| Event | Proceedings of the 2002 IEEE Engineering in Medicine and Biology 24th Annual Conference and the 2002 Fall Meeting of the Biomedical Engineering Society (BMES / EMBS) - Houston, TX, United States Duration: Oct 23 2002 → Oct 26 2002 |
Keywords
- Cytoskeleton
- Microtubules
- Prestress
- Tensegrity
ASJC Scopus subject areas
- Signal Processing
- Health Informatics
- Computer Vision and Pattern Recognition
- Biomedical Engineering