Abstract
We measured cytoskeletal prestress and stiffness in cultured airway smooth muscle cells treated with graded doses of histamine and isoproterenol, and with colchicine. The stiffness increased in proportion with increasing prestress. This feature is the hallmark of systems known as stress-supported structures. In addition, microtubules balanced a substantial, but relatively small fraction of the prestress.
Original language | English (US) |
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Pages (from-to) | 1466-1467 |
Number of pages | 2 |
Journal | Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings |
Volume | 2 |
State | Published - 2002 |
Externally published | Yes |
Keywords
- Cytoskeleton
- Microtubules
- Prestress
- Tensegrity
ASJC Scopus subject areas
- Bioengineering