Abstract

Adaptation has a crucial role in the gradient-sensing mechanism that underlies bacterial chemotaxis. The Escherichia coli chemotaxis pathway uses a single adaptation system involving reversible receptor methylation. In Bacillus subtilis, the chemotaxis pathway seems to use three adaptation systems. One involves reversible receptor methylation, although quite differently than in E. coli. The other two involve CheC, CheD and CheV, which are chemotaxis proteins not found in E. coli. Remarkably, no one system is absolutely required for adaptation or is independently capable of generating adaptation. In this review, we discuss these three novel adaptation systems in B. subtilis and propose a model for their integration.

Original languageEnglish (US)
Pages (from-to)480-487
Number of pages8
JournalTrends in Microbiology
Volume16
Issue number10
DOIs
StatePublished - Oct 1 2008

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Chemotaxis
Bacillus subtilis
Escherichia coli
Methylation
Proteins

ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)
  • Infectious Diseases
  • Virology

Cite this

The three adaptation systems of Bacillus subtilis chemotaxis. / Rao, Christopher V.; Glekas, George D.; Ordal, George W.

In: Trends in Microbiology, Vol. 16, No. 10, 01.10.2008, p. 480-487.

Research output: Contribution to journalReview article

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