TY - JOUR
T1 - The TEM characterization of the lamellar structure of osteoporotic human trabecular bone
AU - Rubin, Matthew Aaron
AU - Jasiuk, Iwona
PY - 2005/10/1
Y1 - 2005/10/1
N2 - The lamellar structure of osteoporotic human trabecular bone was characterized experimentally by means of transmission electron microscopy (TEM). More specifically, the TEM was used to determine if trabecular bone exhibits similar lamellar structural motifs as cortical bone by analyzing unmineralized, mineralized and demineralized bone, and to study the influence of the osteocyte network on the lamellar structure of osteoporotic trabecular bone. Comparison with normal trabecular bone is included. This paper summarizes partial results of a larger study, which addressed the characterization of the hierarchical structure of normal versus osteoporotic human trabecular bone [Rubin, M.A., 2001. Multiscale characterization of the ultrastructure of trabecular bone in osteoporotic and normal humans and in two inbred strains of mice. MS Thesis, Georgia Institute of Technology.] at several structural scales.
AB - The lamellar structure of osteoporotic human trabecular bone was characterized experimentally by means of transmission electron microscopy (TEM). More specifically, the TEM was used to determine if trabecular bone exhibits similar lamellar structural motifs as cortical bone by analyzing unmineralized, mineralized and demineralized bone, and to study the influence of the osteocyte network on the lamellar structure of osteoporotic trabecular bone. Comparison with normal trabecular bone is included. This paper summarizes partial results of a larger study, which addressed the characterization of the hierarchical structure of normal versus osteoporotic human trabecular bone [Rubin, M.A., 2001. Multiscale characterization of the ultrastructure of trabecular bone in osteoporotic and normal humans and in two inbred strains of mice. MS Thesis, Georgia Institute of Technology.] at several structural scales.
KW - Lamellar level
KW - Osteoporosis
KW - Trabecular bone
KW - Transmission electron microscopy
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U2 - 10.1016/j.micron.2005.07.010
DO - 10.1016/j.micron.2005.07.010
M3 - Review article
C2 - 16198582
AN - SCOPUS:28644432483
VL - 36
SP - 653
EP - 664
JO - Zeitschrift fur wissenschaftliche Mikroskopie und mikroskopische Technik
JF - Zeitschrift fur wissenschaftliche Mikroskopie und mikroskopische Technik
SN - 0968-4328
IS - 7-8
ER -