The SERM/SERD bazedoxifene disrupts ESR1 helix 12 to overcome acquired hormone resistance in breast cancer cells

Sean W. Fanning, Rinath Jeselsohn, Venkatasubramanian Dharmarajan, Christopher G. Mayne, Mostafa Karimi, Gilles Buchwalter, René Houtman, Weiyi Toy, Colin E. Fowler, Ross Han, Muriel Lainé, Kathryn E. Carlson, Teresa A. Martin, Jason Nowak, Jerome C. Nwachukwu, David J. Hosfield, Sarat Chandarlapaty, Emad Tajkhorshid, Kendall W. Nettles, Patrick R. GriffinYang Shen, John A. Katzenellenbogen, Myles Brown, Geoffrey L. Greene

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Keyphrases

Pharmacology, Toxicology and Pharmaceutical Science

Biochemistry, Genetics and Molecular Biology