TY - JOUR
T1 - The sequence of a drosophila Cyp4e2 cytochrome p450-encoding cDNA
AU - Pittendrigh, Barry Robert
AU - Mocelin, Giovanni
AU - Andreev, Olga
AU - Ffrench-Constant, Richard H.
PY - 1996/11/14
Y1 - 1996/11/14
N2 - A composite 1458-bp cDNA that encodes cytochrome P450 (P450) Cyp4e2 has been constructed from clones isolated from two Drosophila embryonic cDNA libraries. The Drosophila cDNA open reading frame encodes a protein of 486 amino acids that is 40% identical and 61% similar to Cyp4d1 from Drosophila. The predicted protein is unusual in that it appears to lack the hydrophobic N-terminus typical of microsomal P450s and also contains a small insertion at its C-terminus.
AB - A composite 1458-bp cDNA that encodes cytochrome P450 (P450) Cyp4e2 has been constructed from clones isolated from two Drosophila embryonic cDNA libraries. The Drosophila cDNA open reading frame encodes a protein of 486 amino acids that is 40% identical and 61% similar to Cyp4d1 from Drosophila. The predicted protein is unusual in that it appears to lack the hydrophobic N-terminus typical of microsomal P450s and also contains a small insertion at its C-terminus.
KW - Cytochrome P450
KW - Drosophila
KW - Insecticide resistance
UR - http://www.scopus.com/inward/record.url?scp=0030583732&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0030583732&partnerID=8YFLogxK
U2 - 10.1016/S0378-1119(96)00378-2
DO - 10.1016/S0378-1119(96)00378-2
M3 - Article
C2 - 8972915
AN - SCOPUS:0030583732
SN - 0378-1119
VL - 179
SP - 295
EP - 296
JO - Gene
JF - Gene
IS - 2
ER -