The sequence of a drosophila Cyp4e2 cytochrome p450-encoding cDNA

Barry R. Pittendrigh; Giovanni Mocelin; Olga Andreev; Richard H. Ffrench-Constant

doi:10.1016/S0378-1119(96)00378-2

The sequence of a drosophila Cyp4e2 cytochrome p450-encoding cDNA

Barry R. Pittendrigh, Giovanni Mocelin, Olga Andreev, Richard H. Ffrench-Constant

Research output: Contribution to journal › Article › peer-review

Abstract

A composite 1458-bp cDNA that encodes cytochrome P450 (P450) Cyp4e2 has been constructed from clones isolated from two Drosophila embryonic cDNA libraries. The Drosophila cDNA open reading frame encodes a protein of 486 amino acids that is 40% identical and 61% similar to Cyp4d1 from Drosophila. The predicted protein is unusual in that it appears to lack the hydrophobic N-terminus typical of microsomal P450s and also contains a small insertion at its C-terminus.

Original language	English (US)
Pages (from-to)	295-296
Number of pages	2
Journal	Gene
Volume	179
Issue number	2
DOIs	https://doi.org/10.1016/S0378-1119(96)00378-2
State	Published - Nov 14 1996
Externally published	Yes

Keywords

Cytochrome P450
Drosophila
Insecticide resistance

ASJC Scopus subject areas

Genetics

Online availability

10.1016/S0378-1119(96)00378-2

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AB - A composite 1458-bp cDNA that encodes cytochrome P450 (P450) Cyp4e2 has been constructed from clones isolated from two Drosophila embryonic cDNA libraries. The Drosophila cDNA open reading frame encodes a protein of 486 amino acids that is 40% identical and 61% similar to Cyp4d1 from Drosophila. The predicted protein is unusual in that it appears to lack the hydrophobic N-terminus typical of microsomal P450s and also contains a small insertion at its C-terminus.

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KW - Insecticide resistance

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The sequence of a drosophila Cyp4e2 cytochrome p450-encoding cDNA

Abstract

Keywords

ASJC Scopus subject areas

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