The sequence of a drosophila Cyp4e2 cytochrome p450-encoding cDNA

Barry R. Pittendrigh, Giovanni Mocelin, Olga Andreev, Richard H. Ffrench-Constant

Research output: Contribution to journalArticlepeer-review


A composite 1458-bp cDNA that encodes cytochrome P450 (P450) Cyp4e2 has been constructed from clones isolated from two Drosophila embryonic cDNA libraries. The Drosophila cDNA open reading frame encodes a protein of 486 amino acids that is 40% identical and 61% similar to Cyp4d1 from Drosophila. The predicted protein is unusual in that it appears to lack the hydrophobic N-terminus typical of microsomal P450s and also contains a small insertion at its C-terminus.

Original languageEnglish (US)
Pages (from-to)295-296
Number of pages2
Issue number2
StatePublished - Nov 14 1996
Externally publishedYes


  • Cytochrome P450
  • Drosophila
  • Insecticide resistance

ASJC Scopus subject areas

  • Genetics


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