The role of val⁶⁸(E11) in ligand binding to sperm whale myoglobin: Site-directed mutagenesis of a synthetic gene

Keyphrases

• Site-directed mutagenesis 100%
• Myoglobin 100%
• Ligand Binding 100%
• Sperm Whale 100%
• Synthetic Gene 100%
• Side Chain 80%
• Isocyanide 60%
• Association Rate Constant 60%
• Double mutant 40%
• Dissociation Rate Constant 40%
• O2 Affinity 40%
• Amino Acids 20%
• Size Effect 20%
• Association Constant 20%
• Histidine 20%
• Kinetic Parameters 20%
• Phenylalanine 20%
• Bound States 20%
• Site-directed mutant 20%
• Benzyl 20%
• Flash Photolysis 20%
• Native Protein 20%
• Functional Role 20%
• Iron Atom 20%
• Valine 20%
• Rapid Mixing 20%
• Distal Histidine 20%
• Stopped Flow 20%
• Kinetic Barrier 20%
• Ligand Binding Affinity 20%
• Laser Photolysis 20%
• Alkyl Isocyanides 20%

Biochemistry, Genetics and Molecular Biology

• Site-Directed Mutagenesis 100%
• Myoglobin 100%
• Ligand Binding 100%
• Sperm Whale 100%
• Association Rate Constant 60%
• Histidine 40%
• Oxygen Affinity 40%
• Dissociation Rate Constant 40%
• Amino Acids 20%
• Binding Affinity 20%
• Phenylalanine 20%
• Kinetic Parameter 20%
• Valine 20%
• Photolysis 20%
• Flushing 20%