The role of macromolecular antifreezes in cold water fishes

John G. Duman, Arthur L. DeVries

Research output: Contribution to journalArticlepeer-review


1.Techniques useful in screening the blood serum of fishes for the presence of macromolecular antifreeze compounds are described and discussed.2.Several species of teleost fishes, representing phylogenetically widely divergent families, are shown to have macromolecular anifreeze substances in their blood serum.3.The antifreeze compounds may account for as much as 60% of the freezing depression of the serum.4.The antifreeze substances lower the freezing point of the serum without appreciably depressing the melting point, thereby resulting in a thermal hysteresis.

Original languageEnglish (US)
Pages (from-to)193-199
Number of pages7
JournalComparative Biochemistry and Physiology -- Part A: Physiology
Issue number1
StatePublished - 1975
Externally publishedYes


  • Antarctic fish
  • Antifreeze
  • blood
  • cold water fish

ASJC Scopus subject areas

  • Physiology


Dive into the research topics of 'The role of macromolecular antifreezes in cold water fishes'. Together they form a unique fingerprint.

Cite this