@article{2d5998c256c54e17bb9691d792a51360,
title = "The rise of hierarchy and modularity in biological networks explained by empedocles{\textquoteright} double tale ∼2,400 years before darwin and systems biology",
keywords = "biphasic bow-tie pattern, empedocles, evolutionary diversification, evolutionary growth, hourglass, molecular structure, papyrus, phylogenetic analysis",
author = "Gustavo Caetano-Anoll{\'e}s and Richard Janko",
note = "Funding Information: Systems biology research was supported by a grant from the USDA National Institute of Food and Agriculture (Hatch-1014249) and several Blue Waters supercomputer allocations to GCA. ",
year = "2022",
month = aug,
day = "17",
doi = "10.3389/fgene.2022.973233",
language = "English (US)",
volume = "13",
journal = "Frontiers in Genetics",
issn = "1664-8021",
publisher = "Frontiers Media SA",
}