The Promises and Pitfalls of Small-Molecule Inhibition of Poly(ADP-Ribose) Glycohydrolase (PARG)

Amanda C. Nottbohm, Paul J. Hergenrother

Research output: Chapter in Book/Report/Conference proceedingChapter

Original languageEnglish (US)
Title of host publicationDrug Discovery Research
Subtitle of host publicationNew Frontiers in the Post-Genomic Era
PublisherJohn Wiley & Sons, Inc.
Pages163-185
Number of pages23
ISBN (Print)9780471672005
DOIs
StatePublished - Nov 2 2006

Keywords

  • PARG inhibitors
  • PARG purification and assays
  • Poly(ADP-ribose) polymerases (PARPs)

ASJC Scopus subject areas

  • Chemistry(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)
  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Nottbohm, A. C., & Hergenrother, P. J. (2006). The Promises and Pitfalls of Small-Molecule Inhibition of Poly(ADP-Ribose) Glycohydrolase (PARG). In Drug Discovery Research: New Frontiers in the Post-Genomic Era (pp. 163-185). John Wiley & Sons, Inc.. https://doi.org/10.1002/9780470131862.ch7