The presence of linoleic acid in Escherichia coli cannot be confirmed

J. E. Cronan, C. O. Rock

Research output: Contribution to journalComment/debatepeer-review


Escherichia coli was recently reported to accumulate significant quantities of linoleic acid in stationary phase (H. Rabinowitch, D. D. Sklan, D. H. Chace, R. D. Stevens, and I. Fridovich, J. Bacteriol. 175:5324-5328, 1993). Since this finding would have considerable impact on the biochemical mechanisms of type II fatty acid synthases, we have attempted to confirm this observation. We found no evidence for the accumulation of linoleic acid in late-stationary-phase cultures of E. coli and conclude that the results of Rabinowitch et al. are artifactual.

Original languageEnglish (US)
Pages (from-to)3069-3071
Number of pages3
JournalJournal of bacteriology
Issue number10
StatePublished - 1994
Externally publishedYes

ASJC Scopus subject areas

  • Microbiology
  • Molecular Biology


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