TY - JOUR
T1 - The presence of linoleic acid in Escherichia coli cannot be confirmed
AU - Cronan, J. E.
AU - Rock, C. O.
PY - 1994
Y1 - 1994
N2 - Escherichia coli was recently reported to accumulate significant quantities of linoleic acid in stationary phase (H. Rabinowitch, D. D. Sklan, D. H. Chace, R. D. Stevens, and I. Fridovich, J. Bacteriol. 175:5324-5328, 1993). Since this finding would have considerable impact on the biochemical mechanisms of type II fatty acid synthases, we have attempted to confirm this observation. We found no evidence for the accumulation of linoleic acid in late-stationary-phase cultures of E. coli and conclude that the results of Rabinowitch et al. are artifactual.
AB - Escherichia coli was recently reported to accumulate significant quantities of linoleic acid in stationary phase (H. Rabinowitch, D. D. Sklan, D. H. Chace, R. D. Stevens, and I. Fridovich, J. Bacteriol. 175:5324-5328, 1993). Since this finding would have considerable impact on the biochemical mechanisms of type II fatty acid synthases, we have attempted to confirm this observation. We found no evidence for the accumulation of linoleic acid in late-stationary-phase cultures of E. coli and conclude that the results of Rabinowitch et al. are artifactual.
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U2 - 10.1128/jb.176.10.3069-3071.1994
DO - 10.1128/jb.176.10.3069-3071.1994
M3 - Comment/debate
C2 - 8188608
AN - SCOPUS:0028357474
SN - 0021-9193
VL - 176
SP - 3069
EP - 3071
JO - Journal of bacteriology
JF - Journal of bacteriology
IS - 10
ER -