@article{4615758980324efd8ad764d01546a021,
title = "The lipid composition of the cerebral hemisphere of the miniature pig (Sus scrofa) during development",
abstract = "1. 1. The lipid content of the cerebral hemisphere of the miniature pig (Sus scrofa) has been examined from the eighty-seventh day of gestation through the fourth year of life. 2. 2. The rate of lipid accumulation began to fall rapidly after the forty-seventh day of life, but approximately 30 per cent of the lipid found in the hemisphere of the adult animal is deposited after the sixth month of life. 3. 3. Nearly one-half of the cerebrosides and proteolipid proteins, lipid classes closely associated with myelin, are deposited after 6 months of life.",
keywords = "Miniature pig, Sus scrofa, cerebral development, glycolipids, lipid, proteolipid proteins",
author = "Prensky, {A. L.} and A. Moses and M. Fishman and Tumbleson, {M. E.} and B. Daftari",
note = "Funding Information: INTRODUCTION LIPIDS have long been recognized as important membrane constituents, and the relative increase in the lipid content of the brain during development has been interpreted as an indication that lipid-rich membranes, particularly myelin, are synthesized in large quantities as the brain matures. While Koch & Koch (1913) initiated studies of the lipid content of the nervous system during maturation, Folch-Pi (1955) was the first to accurately measure a number of lipid classes by modern methods and to define the relationship of specific lipids to myelination. Since 1955, the accumulation of lipids in the developing nervous system has been investigated in the mouse (Uzman & Rumley, 1958); rat (Kishimoto et al., 1965; Galli & Re Cecconi, 1967; Wells & Dittmer, 1967; Hauser, 1968; Bass et al., 1969); rabbit (Davison & Wajda, 1959; Dalal & Roboz Einstein, 1969); pig (Dickerson & Dobbing, 1967); and human (Tingey, 1956; Cumings et al., 1958; O'Brien & Sampson, 1965; Lesch, 1969). The present study is concerned with developmental changes in the lipid content of the cerebral hemisphere of the miniature pig. This animal is of special interest from the National Multiple Sclerosis Society; and grants from the Allen P. and Josephine B. Green Foundation, Mexico, Missouri. t Present address: St. Louis Children's Hospital, 500 S. Kingshighway, St. Louis, Missouri 63110.",
year = "1971",
month = aug,
day = "15",
doi = "10.1016/0305-0491(71)90098-8",
language = "English (US)",
volume = "39",
pages = "725--738",
journal = "Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology",
issn = "1096-4959",
number = "4",
}