The influence of posterior parietal cortex on extrastriate visual activity: A concurrent TMS and fast optical imaging study

Nathan A. Parks, Chiara Mazzi, Evelina Tapia, Silvia Savazzi, Monica Fabiani, Gabriele Gratton, Diane M Beck

Research output: Contribution to journalArticle

Abstract

The posterior parietal cortex (PPC) is a critical node in attentional and saccadic eye movement networks of the cerebral cortex, exerting top-down control over activity in visual cortex. Here, we sought to further elucidate the properties of PPC feedback by providing a time-resolved map of functional connectivity between parietal and occipital cortex using single-pulse TMS to stimulate the left PPC while concurrently recording fast optical imaging data from bilateral occipital cortex. Magnetic stimulation of the PPC induced transient ipsilateral occipital activations (BA 18) 24-48. ms post-TMS. Concurrent TMS and fast optical imaging results demonstrate a clear influence of PPC stimulation on activity within human extrastriate visual cortex and further extend this time- and space-resolved method for examining functional connectivity.

Original languageEnglish (US)
Pages (from-to)153-158
Number of pages6
JournalNeuropsychologia
Volume78
DOIs
StatePublished - Nov 1 2015

Fingerprint

Parietal Lobe
Optical Imaging
Visual Cortex
Occipital Lobe
Saccades
Human Activities
Cerebral Cortex

Keywords

  • Brain connectivity
  • Event-related optical signal (EROS)
  • Near-infrared optical imaging
  • Phosphene
  • Posterior parietal cortex
  • Transcranial magnetic stimulation (TMS)

ASJC Scopus subject areas

  • Experimental and Cognitive Psychology
  • Cognitive Neuroscience
  • Behavioral Neuroscience

Cite this

The influence of posterior parietal cortex on extrastriate visual activity : A concurrent TMS and fast optical imaging study. / Parks, Nathan A.; Mazzi, Chiara; Tapia, Evelina; Savazzi, Silvia; Fabiani, Monica; Gratton, Gabriele; Beck, Diane M.

In: Neuropsychologia, Vol. 78, 01.11.2015, p. 153-158.

Research output: Contribution to journalArticle

@article{a9b9daa5f7ca4848a75652654759c105,
title = "The influence of posterior parietal cortex on extrastriate visual activity: A concurrent TMS and fast optical imaging study",
abstract = "The posterior parietal cortex (PPC) is a critical node in attentional and saccadic eye movement networks of the cerebral cortex, exerting top-down control over activity in visual cortex. Here, we sought to further elucidate the properties of PPC feedback by providing a time-resolved map of functional connectivity between parietal and occipital cortex using single-pulse TMS to stimulate the left PPC while concurrently recording fast optical imaging data from bilateral occipital cortex. Magnetic stimulation of the PPC induced transient ipsilateral occipital activations (BA 18) 24-48. ms post-TMS. Concurrent TMS and fast optical imaging results demonstrate a clear influence of PPC stimulation on activity within human extrastriate visual cortex and further extend this time- and space-resolved method for examining functional connectivity.",
keywords = "Brain connectivity, Event-related optical signal (EROS), Near-infrared optical imaging, Phosphene, Posterior parietal cortex, Transcranial magnetic stimulation (TMS)",
author = "Parks, {Nathan A.} and Chiara Mazzi and Evelina Tapia and Silvia Savazzi and Monica Fabiani and Gabriele Gratton and Beck, {Diane M}",
year = "2015",
month = "11",
day = "1",
doi = "10.1016/j.neuropsychologia.2015.10.002",
language = "English (US)",
volume = "78",
pages = "153--158",
journal = "Neuropsychologia",
issn = "0028-3932",
publisher = "Elsevier Limited",

}

TY - JOUR

T1 - The influence of posterior parietal cortex on extrastriate visual activity

T2 - A concurrent TMS and fast optical imaging study

AU - Parks, Nathan A.

AU - Mazzi, Chiara

AU - Tapia, Evelina

AU - Savazzi, Silvia

AU - Fabiani, Monica

AU - Gratton, Gabriele

AU - Beck, Diane M

PY - 2015/11/1

Y1 - 2015/11/1

N2 - The posterior parietal cortex (PPC) is a critical node in attentional and saccadic eye movement networks of the cerebral cortex, exerting top-down control over activity in visual cortex. Here, we sought to further elucidate the properties of PPC feedback by providing a time-resolved map of functional connectivity between parietal and occipital cortex using single-pulse TMS to stimulate the left PPC while concurrently recording fast optical imaging data from bilateral occipital cortex. Magnetic stimulation of the PPC induced transient ipsilateral occipital activations (BA 18) 24-48. ms post-TMS. Concurrent TMS and fast optical imaging results demonstrate a clear influence of PPC stimulation on activity within human extrastriate visual cortex and further extend this time- and space-resolved method for examining functional connectivity.

AB - The posterior parietal cortex (PPC) is a critical node in attentional and saccadic eye movement networks of the cerebral cortex, exerting top-down control over activity in visual cortex. Here, we sought to further elucidate the properties of PPC feedback by providing a time-resolved map of functional connectivity between parietal and occipital cortex using single-pulse TMS to stimulate the left PPC while concurrently recording fast optical imaging data from bilateral occipital cortex. Magnetic stimulation of the PPC induced transient ipsilateral occipital activations (BA 18) 24-48. ms post-TMS. Concurrent TMS and fast optical imaging results demonstrate a clear influence of PPC stimulation on activity within human extrastriate visual cortex and further extend this time- and space-resolved method for examining functional connectivity.

KW - Brain connectivity

KW - Event-related optical signal (EROS)

KW - Near-infrared optical imaging

KW - Phosphene

KW - Posterior parietal cortex

KW - Transcranial magnetic stimulation (TMS)

UR - http://www.scopus.com/inward/record.url?scp=84944050070&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84944050070&partnerID=8YFLogxK

U2 - 10.1016/j.neuropsychologia.2015.10.002

DO - 10.1016/j.neuropsychologia.2015.10.002

M3 - Article

C2 - 26449990

AN - SCOPUS:84944050070

VL - 78

SP - 153

EP - 158

JO - Neuropsychologia

JF - Neuropsychologia

SN - 0028-3932

ER -