The effects of sodium bicarbonate administered nasogastrically on plasma volume, electrolytes and blood gases in resting quarter horses

C. M. Hanson, K. H. Kline, J. H. Foreman, L. P. Frey

Research output: Contribution to journalArticlepeer-review

Abstract

The purpose of this study was to investigate the effect of a single dose (1000 mg/kg of body weight) of sodium bicarbonate (NaHC03) on plasma volume, pH, HC03 concentration, and serum Na, Cl, K, and Ca levels. Eight Quarter Horse mares, ranging in age from 5 to 15 years, were paired into four groups and used in a four-period crossover experiment. Each pair of horses was randomly assigned each week to one of four treatments: H20 only (A), NaHC03 with H20 (B), no NaHC03 with no H20 (C), and NaHC03 without H20 (D). Plasma volumes were determined by using an Evan's Blue Dye dilution technique. Mean plasma volume was 16.01, and no significant difference (p > 0.05) was found between treatments. Blood gases and pH were determined before and six hours after NaHC03 administration. Analysis of variance found that treatments B and D significantly (p > 0.01) affected levels of pH, pC02, P02, HC03, Na, Cl, Ca and K compared to both treatments A and C.

Original languageEnglish (US)
Pages (from-to)593-596
Number of pages4
JournalJournal of Equine Veterinary Science
Volume13
Issue number10
DOIs
StatePublished - Jan 1 1993

Keywords

  • Alkalosis
  • Blood Gases
  • Plasma Volume
  • Sodium Bicarbonate

ASJC Scopus subject areas

  • Equine

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