The sophistication of malicious adversaries is increasing every day and most defenses are often easily overcome by such attackers. Many existing defensive mechanisms often make differing assumptions about the underlying systems and use varied architectures to implement their solutions. This often leads to fragmentation among solutions and could even open up additional vulnerabilities in the system. We present the DragonBeam Framework that enables system designers to implement their own monitoring methods and analyses engines to detect intrusions in modern operating systems. It is built upon a novel hardware/software mechanism. Depending on the type of monitoring that is implemented using this framework, the impact on the monitored system is very low. This is demonstrated by the use cases presented in this paper that also showcase how the DragonBeam framework can be used to detect different types of attack.