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The dimeric structure of factor XI and zymogen activation
Yipeng Geng
, Ingrid M. Verhamme
, Stephen B. Smith
, Mao fu Sun
, Anton Matafonov
, Qiufang Cheng
, Stephanie A. Smith
, James H. Morrissey
, David Gailani
Biochemistry
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Keyphrases
Thrombin
100%
Dimeric Structure
100%
Zymogen Activation
100%
Factor XIIa
85%
Protease
57%
Autoactivation
42%
Polyps
42%
Activation Mechanism
28%
Platelets
14%
Gene-deficient Mice
14%
Transactivation
14%
Polyanion
14%
Phosphorus-containing Polymers
14%
Homodimeric
14%
Zymogen
14%
FXIIa
14%
Thrombosis Model
14%
Pharmacology, Toxicology and Pharmaceutical Science
Enzyme Precursor
100%
Blood Clotting Factor 11
100%
Thrombin
58%
Proteinase
33%
Monomer
16%
Dimer
16%
Polyanion
8%
Thrombosis
8%
Biochemistry, Genetics and Molecular Biology
Zymogen
100%
Factor XI
100%
Thrombin
58%
Protease
33%
Transactivation
8%
Platelet
8%