The complete genome of the hyperthermophilic bacterium Aquifex aeolicus

Gerard Deckert, Patrick V. Warren, Terry Gaasterland, William G. Young, Anna L. Lenox, David E. Graham, Ross Overbeek, Marjory A. Snead, Martin Keller, Monette Aujay, Robert Huber, Robert A. Feldman, Jay M. Short, Gary J Olsen, Ronald V. Swanson

Research output: Contribution to journalArticle

Abstract

Aquifex aeolicus was one of the earliest diverging, and is one of the most thermophilic, bacteria known. It can grow on hydrogen, oxygen, carbon dioxide, and mineral salts. The complex metabolic machinery needed for A. aeolicus to function as a chemolithoautotroph (an organism which uses an inorganic carbon source for biosynthesis and an inorganic chemical energy source) is encoded within a genome that is only one-third the size of the E. coli genome. Metabolic flexibility seems to be reduced as a result of the limited genome size. The use of oxygen (albeit at very low concentrations) as an electron acceptor is allowed by the presence of a complex respiratory apparatus. Although this organism grows at 95°C, the extreme thermal limit of the Bacteria, only a few specific indications of thermophily are apparent from the genoma. Here we describe the complete genoma sequence of 1,551,335 base pairs of this evolutionarily and physiologically interesting organism.

Original languageEnglish (US)
Pages (from-to)353-358
Number of pages6
JournalNature
Volume392
Issue number6674
DOIs
StatePublished - Mar 26 1998

Fingerprint

Inorganic Chemicals
Extreme Heat
Genome
Oxygen
Bacteria
Genome Size
Carbon Dioxide
Base Pairing
Minerals
Hydrogen
Carbon
Salts
Electrons
Escherichia coli

ASJC Scopus subject areas

  • General

Cite this

Deckert, G., Warren, P. V., Gaasterland, T., Young, W. G., Lenox, A. L., Graham, D. E., ... Swanson, R. V. (1998). The complete genome of the hyperthermophilic bacterium Aquifex aeolicus. Nature, 392(6674), 353-358. https://doi.org/10.1038/32831

The complete genome of the hyperthermophilic bacterium Aquifex aeolicus. / Deckert, Gerard; Warren, Patrick V.; Gaasterland, Terry; Young, William G.; Lenox, Anna L.; Graham, David E.; Overbeek, Ross; Snead, Marjory A.; Keller, Martin; Aujay, Monette; Huber, Robert; Feldman, Robert A.; Short, Jay M.; Olsen, Gary J; Swanson, Ronald V.

In: Nature, Vol. 392, No. 6674, 26.03.1998, p. 353-358.

Research output: Contribution to journalArticle

Deckert, G, Warren, PV, Gaasterland, T, Young, WG, Lenox, AL, Graham, DE, Overbeek, R, Snead, MA, Keller, M, Aujay, M, Huber, R, Feldman, RA, Short, JM, Olsen, GJ & Swanson, RV 1998, 'The complete genome of the hyperthermophilic bacterium Aquifex aeolicus', Nature, vol. 392, no. 6674, pp. 353-358. https://doi.org/10.1038/32831
Deckert G, Warren PV, Gaasterland T, Young WG, Lenox AL, Graham DE et al. The complete genome of the hyperthermophilic bacterium Aquifex aeolicus. Nature. 1998 Mar 26;392(6674):353-358. https://doi.org/10.1038/32831
Deckert, Gerard ; Warren, Patrick V. ; Gaasterland, Terry ; Young, William G. ; Lenox, Anna L. ; Graham, David E. ; Overbeek, Ross ; Snead, Marjory A. ; Keller, Martin ; Aujay, Monette ; Huber, Robert ; Feldman, Robert A. ; Short, Jay M. ; Olsen, Gary J ; Swanson, Ronald V. / The complete genome of the hyperthermophilic bacterium Aquifex aeolicus. In: Nature. 1998 ; Vol. 392, No. 6674. pp. 353-358.
@article{32285bf877d5429d95df620c9cbaaa03,
title = "The complete genome of the hyperthermophilic bacterium Aquifex aeolicus",
abstract = "Aquifex aeolicus was one of the earliest diverging, and is one of the most thermophilic, bacteria known. It can grow on hydrogen, oxygen, carbon dioxide, and mineral salts. The complex metabolic machinery needed for A. aeolicus to function as a chemolithoautotroph (an organism which uses an inorganic carbon source for biosynthesis and an inorganic chemical energy source) is encoded within a genome that is only one-third the size of the E. coli genome. Metabolic flexibility seems to be reduced as a result of the limited genome size. The use of oxygen (albeit at very low concentrations) as an electron acceptor is allowed by the presence of a complex respiratory apparatus. Although this organism grows at 95°C, the extreme thermal limit of the Bacteria, only a few specific indications of thermophily are apparent from the genoma. Here we describe the complete genoma sequence of 1,551,335 base pairs of this evolutionarily and physiologically interesting organism.",
author = "Gerard Deckert and Warren, {Patrick V.} and Terry Gaasterland and Young, {William G.} and Lenox, {Anna L.} and Graham, {David E.} and Ross Overbeek and Snead, {Marjory A.} and Martin Keller and Monette Aujay and Robert Huber and Feldman, {Robert A.} and Short, {Jay M.} and Olsen, {Gary J} and Swanson, {Ronald V.}",
year = "1998",
month = "3",
day = "26",
doi = "10.1038/32831",
language = "English (US)",
volume = "392",
pages = "353--358",
journal = "Nature",
issn = "0028-0836",
publisher = "Nature Publishing Group",
number = "6674",

}

TY - JOUR

T1 - The complete genome of the hyperthermophilic bacterium Aquifex aeolicus

AU - Deckert, Gerard

AU - Warren, Patrick V.

AU - Gaasterland, Terry

AU - Young, William G.

AU - Lenox, Anna L.

AU - Graham, David E.

AU - Overbeek, Ross

AU - Snead, Marjory A.

AU - Keller, Martin

AU - Aujay, Monette

AU - Huber, Robert

AU - Feldman, Robert A.

AU - Short, Jay M.

AU - Olsen, Gary J

AU - Swanson, Ronald V.

PY - 1998/3/26

Y1 - 1998/3/26

N2 - Aquifex aeolicus was one of the earliest diverging, and is one of the most thermophilic, bacteria known. It can grow on hydrogen, oxygen, carbon dioxide, and mineral salts. The complex metabolic machinery needed for A. aeolicus to function as a chemolithoautotroph (an organism which uses an inorganic carbon source for biosynthesis and an inorganic chemical energy source) is encoded within a genome that is only one-third the size of the E. coli genome. Metabolic flexibility seems to be reduced as a result of the limited genome size. The use of oxygen (albeit at very low concentrations) as an electron acceptor is allowed by the presence of a complex respiratory apparatus. Although this organism grows at 95°C, the extreme thermal limit of the Bacteria, only a few specific indications of thermophily are apparent from the genoma. Here we describe the complete genoma sequence of 1,551,335 base pairs of this evolutionarily and physiologically interesting organism.

AB - Aquifex aeolicus was one of the earliest diverging, and is one of the most thermophilic, bacteria known. It can grow on hydrogen, oxygen, carbon dioxide, and mineral salts. The complex metabolic machinery needed for A. aeolicus to function as a chemolithoautotroph (an organism which uses an inorganic carbon source for biosynthesis and an inorganic chemical energy source) is encoded within a genome that is only one-third the size of the E. coli genome. Metabolic flexibility seems to be reduced as a result of the limited genome size. The use of oxygen (albeit at very low concentrations) as an electron acceptor is allowed by the presence of a complex respiratory apparatus. Although this organism grows at 95°C, the extreme thermal limit of the Bacteria, only a few specific indications of thermophily are apparent from the genoma. Here we describe the complete genoma sequence of 1,551,335 base pairs of this evolutionarily and physiologically interesting organism.

UR - http://www.scopus.com/inward/record.url?scp=0032568375&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032568375&partnerID=8YFLogxK

U2 - 10.1038/32831

DO - 10.1038/32831

M3 - Article

C2 - 9537320

AN - SCOPUS:0032568375

VL - 392

SP - 353

EP - 358

JO - Nature

JF - Nature

SN - 0028-0836

IS - 6674

ER -