The berry health tool chest-an evidence map and interactive resource

Kristine L. Kay, Renee C. Strauch, Cheryl D. Granillo, Megan W. Bame, Jia Xiong, Aubrey C. Mast, Britt Burton-Freeman, Colin D. Kay, Mary Ann Lila

Research output: Contribution to journalReview articlepeer-review


Berry consumption is linked to diverse health benefits, but numerous questions remain regarding mechanism of action, dose efficacy, and optimal duration and frequency of intake. Addressing these outstanding questions requires an organized assessment of current research, to inform future study designs and fill critical knowledge gaps. Tools that organize such information will also facilitate consumer messaging, targeted nutritional health initiatives, and dietary intake guidelines. This review aimed to describe the development and utility of the "Berry Health Tool Chest,"an evidence map summarizing trial design features of studies characterizing the impact of berry consumption upon human health biomarkers. A systematic search strategy identified relevant high-quality human feeding studies, whose study design parameters were collected and compiled into an evidence map that is freely available as an interactive online interface enabling tabulated data to be interrogated, filtered, and exported. Of the 231 included studies, approximately 70% were of less than 3 months' duration and/or fewer than 50 participants, illustrating research gaps that could potentially inform the design of future studies.

Original languageEnglish (US)
Pages (from-to)68-77
Number of pages10
JournalNutrition reviews
Issue number1
StatePublished - Jan 1 2022


  • berry
  • clinical trial design
  • dietary intervention
  • evidence mapping
  • health criteria

ASJC Scopus subject areas

  • Nutrition and Dietetics
  • Medicine (miscellaneous)


Dive into the research topics of 'The berry health tool chest-an evidence map and interactive resource'. Together they form a unique fingerprint.

Cite this