The association between N-methylglucamine antimoniate and pancreatitis in dogs with leishmaniasis

A. Boari, M. Pierantozzi, G. Aste, S. Pantaleo, F. Di Silverio, G. Fanini, L. Lorentzen, D. A. Williams

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

In this study, the possible association between pancreatitis and treatment with methylglucamine antimoniate (MA) in dogs with leishmaniasis was evaluated. Of the 20 dogs included, three dogs showed clinical signs of pancreatitis. Abdominal ultrasound abnormalities suggestive of pancreatitis were observed in two dogs, and increased cPLI was observed in four cases. The statistical results showed a low probability of development of pancreatitis in patients treated with MA. However, considering the possible recurrence of pancreatitis in four cases in our study, we suggest that dogs treated with MA should be evaluated for pancreatitis, especially when compatible clinical signs are present.

Original languageEnglish (US)
Title of host publicationVeterinary Science
Subtitle of host publicationCurrent Aspects in Biology, Animal Pathology, Clinic and Food Hygiene
PublisherSpringer
Pages65-69
Number of pages5
Volume9783642232718
ISBN (Electronic)9783642232718
ISBN (Print)3642232701, 9783642232701
DOIs
StatePublished - Mar 1 2012

Keywords

  • Dog
  • Leishmaniasis
  • Meglumine antimoniate
  • Pancreatitis

ASJC Scopus subject areas

  • General Agricultural and Biological Sciences

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