The action of testosterone at the cell level. Testosterone stimulation of the respiration of Euglena gracilis

D. E. Buetow, B. H. Levedahl

Research output: Contribution to journalArticle

Abstract

The respiration rate of Euglena in the presence of 2.0 μg. or 0.1 μg. testosterone/ml. medium is about 20 and 14% higher, respectively, than that of controls lacking the steroid. This result obtains whether or not the cells were previously grown in the presence of testosterone. Further, the increased respiration rate of Euglena in the presence of testosterone is dependent upon the presence of a nitrogen source. The testosterone "effect" is reduced when nitrogen is absent from the respiration medium and is restored when nitrogen is reintroduced into the medium. The data suggest that an early effect of this steroid on Euglena is on the permeability of these cells to nitrogen-containing compounds with a resultant effect on protein metabolism.

Original languageEnglish (US)
Pages (from-to)358-363
Number of pages6
JournalArchives of Biochemistry and Biophysics
Volume94
Issue number3
DOIs
StatePublished - Sep 1961
Externally publishedYes

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ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology

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