Testis physiology-overview and histology

Nathália L.M. Lara, Guilherme M.J. Costa, Gleide F. Avelar, Samyra M.S.N. Lacerda, Rex A. Hess, Luiz R. França

Research output: Chapter in Book/Report/Conference proceedingChapter


In this article, we cover the main aspects related to testis structure and function, particularly those related to germ cells and support cells present in the seminiferous epithelium and cytoarchitecture of steroidogenic Leydig cells located in the intertubular compartment. A brief description of spermatogenesis, from undifferentiated spermatogonia to sperm formation, as well the organization of germ cells in stages of the seminiferous epithelial cycle and its duration, is also presented. Finally, we describe the key functions accomplished by Sertoli and Leydig cells and the most important parameters related to the magnitude of sperm production in different mammalian species.

Original languageEnglish (US)
Title of host publicationEncyclopedia of Reproduction
Number of pages12
ISBN (Electronic)9780128151457
StatePublished - Jan 1 2018


  • Androgens
  • Duration of spermatogenesis
  • Germ cell
  • Leydig cell
  • Seminiferous epithelium cycle
  • Sertoli cell
  • Sertoli cell barrier
  • Sertoli cell efficiency
  • Sperm production
  • Spermatogenesis
  • Steroidogenesis
  • Testis function
  • Testis structure

ASJC Scopus subject areas

  • Medicine(all)


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