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Targeting Specificity of the CRISPR/Cas9 System
Ipek Tasan,
Huimin Zhao
Chemical and Biomolecular Engineering
Carl R. Woese Institute for Genomic Biology
Bioengineering
Chemistry
Biomedical and Translational Sciences
Research output
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Review article
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peer-review
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Keyphrases
CRISPR-Cas9 System
100%
Cas9 Protein
100%
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)
100%
Target Specificity
100%
Cell-based
50%
High Specificity
50%
Genome Editing
50%
Predictive Algorithm
50%
Therapeutic Potential
50%
Detection Accuracy
50%
Site-directed mutation
50%
Mechanistic Understanding
50%
Gene Correction
50%
Off-target Sites
50%
Cell-free
50%
Donor DNA
50%
Consensus Protocol
50%
Insertional mutagenesis
50%
CRISPR Specificity
50%
Off-target Events
50%
Off-target Analysis
50%
Off-target Detection
50%
Biochemistry, Genetics and Molecular Biology
CRISPR/Cas9
100%
CRISPR
75%
Genome Editing
25%
Insertional Mutagenesis
25%
Neuroscience
CRISPR
100%
Mutagenesis
14%
Pharmacology, Toxicology and Pharmaceutical Science
Mutagenesis
100%
Agricultural and Biological Sciences
Insertional Mutagenesis
100%