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Targeted gene activation using RNA-guided nucleases
Alexander Brown
, Wendy S. Woods
,
Pablo Perez-Pinera
Bioengineering
Carl R. Woese Institute for Genomic Biology
Biomedical and Translational Sciences
Molecular and Integrative Physiology
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peer-review
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Keyphrases
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)
100%
RNA-guided nuclease
100%
Targeted Gene Activation
100%
Gene Delivery
50%
Adaptation
50%
Transcription Factor
50%
Design Considerations
50%
Target Gene Expression
50%
Genetic Engineering
50%
Synthetic Transcription Factor
50%
Transcriptional Repressor
50%
Customizable
50%
Mammalian Cell Lines
50%
Plasmid Construction
50%
Associated System
50%
Targeted Manipulation
50%
Biochemistry, Genetics and Molecular Biology
RNA
100%
Gene Activation
100%
CRISPR
100%
Nuclease
100%
Transcription Factors
50%
Plasmid
25%
Gene Targeting
25%
Gene Expression
25%
Genome Editing
25%
Cas9
25%
Transcriptional Activator
25%