Tamoxifen and 4-hydroxytamoxifen-activated system for regulated production of proteins in eukaryotic cells

Chengjian Mao (Inventor), David J Shapiro (Inventor)

Research output: Patent

Abstract

Novel tamoxifen inducible and ICI 182,780 repressible expression systems comprising mutant estrogen receptors and mutant estrogen response element are disclosed. Such systems have a wide variety of applications, including gene therapy and in vivo and in vitro expression, as well as their use in transgenic animals.
Original languageEnglish (US)
U.S. patent number7153685
StatePublished - Dec 26 2006

Fingerprint

Dive into the research topics of 'Tamoxifen and 4-hydroxytamoxifen-activated system for regulated production of proteins in eukaryotic cells'. Together they form a unique fingerprint.

Cite this