Tamoxifen and 4-hydroxytamoxifen-activated system for regulated production of proteins in eukaryotic cells

Chengjian Mao; David J Shapiro

Tamoxifen and 4-hydroxytamoxifen-activated system for regulated production of proteins in eukaryotic cells

Chengjian Mao (Inventor), David J Shapiro (Inventor)

Research output: Patent

Abstract

Novel tamoxifen inducible and ICI 182,780 repressible expression systems comprising mutant estrogen receptors and mutant estrogen response element are disclosed. Such systems have a wide variety of applications, including gene therapy and in vivo and in vitro expression, as well as their use in transgenic animals.

Original language	English (US)
U.S. patent number	7153685
Filing date	3/11/02
State	Published - Dec 26 2006

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title = "Tamoxifen and 4-hydroxytamoxifen-activated system for regulated production of proteins in eukaryotic cells",

abstract = "Novel tamoxifen inducible and ICI 182,780 repressible expression systems comprising mutant estrogen receptors and mutant estrogen response element are disclosed. Such systems have a wide variety of applications, including gene therapy and in vivo and in vitro expression, as well as their use in transgenic animals.",

author = "Chengjian Mao and Shapiro, {David J}",

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AU - Mao, Chengjian

AU - Shapiro, David J

PY - 2006/12/26

Y1 - 2006/12/26

N2 - Novel tamoxifen inducible and ICI 182,780 repressible expression systems comprising mutant estrogen receptors and mutant estrogen response element are disclosed. Such systems have a wide variety of applications, including gene therapy and in vivo and in vitro expression, as well as their use in transgenic animals.

AB - Novel tamoxifen inducible and ICI 182,780 repressible expression systems comprising mutant estrogen receptors and mutant estrogen response element are disclosed. Such systems have a wide variety of applications, including gene therapy and in vivo and in vitro expression, as well as their use in transgenic animals.

M3 - Patent

M1 - 7153685

Y2 - 2002/03/11

ER -

Tamoxifen and 4-hydroxytamoxifen-activated system for regulated production of proteins in eukaryotic cells

Abstract

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