Abstract
Novel tamoxifen inducible and ICI 182,780 repressible expression systems comprising mutant estrogen receptors and mutant estrogen response element are disclosed. Such systems have a wide variety of applications, including gene therapy and in vivo and in vitro expression, as well as their use in transgenic animals.
Original language | English (US) |
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U.S. patent number | 7153685 |
Filing date | 3/11/02 |
State | Published - Dec 26 2006 |